Massive Skull Metastasis From Follicular Thyroid Carcinoma − How Ignorance Can Harm Your Health

Gandhoke, Charandeep Singh; Borde, Pravin; Syal, Simran K; Singh, Daljit; Saran, Ravindra Kumar; Gupta, Rakesh Kumar

doi:10.4103/mamcjms.mamcjms_38_17

Cited by 3 publications

(2 citation statements)

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“…Similar observations were found by other researchers also where skull metastases from thyroid follicular carcinoma occurred. [22][23][24] Literature and our observations suggest that these tumors are more common in females compared with males. The most favorable site for these tumors is midline of the frontal and parietooccipital region.…”

Section: Metastatic Tumorssupporting

confidence: 51%

Differential Diagnosis of Calvarial Tumors: A Series of 8 Cases

Sharma

Kataria

Choudhary

et al. 2021

Indian Journal of Neurosurgery

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Introduction To present and discuss the clinical presentations, investigations, and treatment options for skull bone tumors. Materials and Methods This study was conducted from January 2019 to December 2019 at the Department of Neurosurgery. During this period, eight patients presented with skull bone tumor in the outpatient department. All patients were thoroughly investigated. Surgery was conducted on six patients and two patients had disseminated carcinoma; hence, surgery was not done. Patients were regularly followed-up after the surgery. Results In our study, out of eight cases, five were females and three were males. We had two cases of fibrous dysplasia, two cases of osteomas, and one case each of brown tumor, metastases from lung carcinoma, metastases from follicular carcinoma of thyroid, and Ewing sarcoma/primitive neuroectodermal tumor (PNET). Excision of tumor was performed where indicated and adjuvant chemo- and radiotherapy was suggested wherever required. Conclusion Bony tumors of the skull are uncommon diseases for the neurosurgeons. These tumors require a careful diagnosis with suitable radiological examinations and proper clinical correlation for proper management.

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Section: Metastatic Tumorssupporting

confidence: 51%

Differential Diagnosis of Calvarial Tumors: A Series of 8 Cases

Sharma

Kataria

Choudhary

et al. 2021

Indian Journal of Neurosurgery

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“…Flat bones such as the scapula, sternum and irregular bones like the ilium, vertebrae, and long bones are mostly affected (2,10). By contrast, skull metastasis in FTC is extremely rare and has been reported in only a few case reports (7,11,12). Most authors found a single, quite large and protruding metastatic lesion in the skull, but there is only one report of multiple skull metastases (13).…”

Section: Discussion and Literature Reviewmentioning

confidence: 99%

Follicular Thyroid Carcinoma Metastasis to the Skull and Brain: Case Series with Literature Review

Bailey¹,

Ali²,

Ferdous³

et al. 2023

Bangladesh J. Nuclear Med.

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Distant metastasis is more common in follicular thyroid carcinomas (FTC) than papillary thyroid carcinomas (PTC), as vascular invasion is often characteristic of FTC. Lung, bone, brain, liver, bladder, and skin are potential sites of distant metastases. On the other hand, lymph node involvement is much less common (8–10%) in cases of FTC compared to PTC. The therapy of patients may be significantly impacted by learning more about the epidemiological features of thyroid metastases at uncommon sites. In our experience, metastases in uncommon sites do not always indicate a poor prognosis for differentiated thyroid carcinoma (DTC), which might be due to the disease patterns. Every year, around 5% new FTC patients are registered, treated with radioiodine, and followed up in the thyroid division of National Institute of Nuclear Medicine and Allied Sciences (NINMAS). Four FTC patients (F=3, M=1) with skull bone and brain metastases are discussed in this case series. All of them were post thyroidectomized and were referred to NINMAS for radioiodine ablation therapy (RAIT). Two of them had skull and brain metastases, third patient had extensive skull, facial bone and pubic bone invasion, whereas, fourth patient had multiple skull metastases. Bangladesh J. Nuclear Med. 25(2): 128-137, 2022

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