Massive pulmonary embolism

Turnier, Edgard; Hill, J. Donald; Kerth, William J.; Gerbode, Frank

doi:10.1016/0002-9610(73)90148-7

Cited by 38 publications

(19 citation statements)

References 28 publications

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“…Of the patients dying as a consequence of pulmonary embolism about 50% are dead within two hours (Roseniberg et al, 1964;Turnier et al, 1973). All except one of the patients in this trial began treatment more than six hours af,ter the major episode.…”

Section: Discussionmentioning

confidence: 92%

“…Pulmonary embolectomy with cardiopulmonary bypass still carries a significant mortality though this is gradually being reduced. Cross and Mowlem (1967) and Turnier et al (1973) reported operative mortalities of 57% and 29% respectively. Tihe operative mortality at the Bromnton Hospital from 1968 to 1971 was 23% in patients undergoing pulmonary embolectomy as ithe initial treatment (Miller, 1972).…”

Section: Discussionmentioning

confidence: 99%

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Comparison by Controlled Clinical Trial of Streptokinase and Heparin in Treatment of Life-threatening Pulmonary Embolism

Tibbutt¹,

Davies²,

Anderson³

et al. 1974

BMJ

239

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SummaryTreatment with heparin or streptokinase was allocated randomly to 30 patients with life-threatening pulmonary embol'sm verified by angiography. Treatment was given for 72 hours and pulmonary angiography was repeated. There was significantly greater (P <0001) evidence of thrombolysis in those patients treated with streptokinase compared with those treated with heparin. The reduction of systolic and mean pulmonary arterial pressures was also significantly greater (P < 0 05 and P < 0-02 respectively) in the streptokinase group.Seven patients failed to complete 72 hours of the trial treatment: five successfully underwent pulmonary embolectomy. Six of these "failures" had initial pulmonary angiographic scores of 24 or more and systemic systolic blood pressure recordings of 100 mm Hg or less. Patients with these features should probably be considered for pulmonary embolectomy as the initial treatment.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Comparison by Controlled Clinical Trial of Streptokinase and Heparin in Treatment of Life-threatening Pulmonary Embolism

Tibbutt¹,

Davies²,

Anderson³

et al. 1974

BMJ

239

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“…29 Stein et al analyzed 1 300 cases of pulmonary embolectomy, collected from 46 reports from 1961 to 2006. 30 They reported mortality of 32% for patients operated on before 1985 versus 20% for those operated on between 1985 and 2005.…”

Section: Mortality and Morbidity Of Acute Pulmonary Embolectomymentioning

confidence: 99%

Embolectomy for acute pulmonary thromboembolism: From Trendelenburg’s procedure to the contemporary surgical approach

Fukuda

Taniguchi

2010

Surg Today

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Acute pulmonary thromboembolism (APTE) is a potentially catastrophic event after surgery. We reviewed the literature on surgical pulmonary embolectomy to elucidate its place in emergency management. Although pulmonary embolectomy is invasive, prompt removal of the emboli decreases the right ventricular load and promotes quick recovery of cardiopulmonary function. Conversely, fibrinolytic therapy places additional burden on patients at risk of potential hemorrhagic complication. Surgical embolectomy is an effective procedure with a low risk of hemorrhage because anticoagulant therapy is needed for only a short time.

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“…Stein et al found that PE frequency increased linearly with age and was more frequent in females over 50 y of age [31]. On the other hand, conversely, Miniati et al reported that male gender was one of the leading factors in increasing PE risk [16].…”

Section: Discussionmentioning

confidence: 99%

“…The main goal of the diagnostic approach is to reduce the need for pulmonary angiography, is the gold standard for PE, as ISSN 0970-938X www.biomedres.info much as possible, which is invasive, expensive, not always easily accessible, and has certain morbidity and mortality for the treatment decision by using non-invasive methods as combination. For this purpose, different diagnostic algorithms including various diagnosis methods such as empirical clinical evaluation, d-dimer, lower extremity ultrasonography (USG), serial venous USG, ventilation-perfusion (V/Q) scintigraphy and computerized tomography pulmonary angiography (CTPA) [15,16].…”

Section: Introductionmentioning

confidence: 99%

The effect of neutrophil/lymphocyte ratio on 1-year mortality in pulmonary embolism diagnosed patients

Urnal¹,

Akyol²,

Karakaya³

et al. 2018

biomedicalresearch

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Background: Pulmonary embolism (PE) is one of the major causes of mortality, morbidity and hospitalizations. We aimed to investigate the effect of neutrophil/lymphocyte ratio (NLR) on 1-year mortality. Material and methods: Among the patients, were referred to the emergency department of our hospital within 1-year who underwent computed tomography pulmonary angiography (CTPA), patients who were interpreted as PE after CTPA were included in the study. Results: The optimal NLR cutoff value for the power in predict 1-year mortality was determined as 4.74 with ROC analysis. The NLR cutoff value of 4.74 had sensitivity of 61%, specificity of 75%. There were statistically significant differences between groups in terms of NLR on 1-year mortality and mortality in patients with a NLR greater than 4.74 was statistically significant higher than in patients with a NLR of 4.74 or less. Conclusion: We believe that NLR can be used in evaluating 1-year mortality of pulmonary embolism.

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Massive pulmonary embolism

Cited by 38 publications

References 28 publications

Comparison by Controlled Clinical Trial of Streptokinase and Heparin in Treatment of Life-threatening Pulmonary Embolism

Comparison by Controlled Clinical Trial of Streptokinase and Heparin in Treatment of Life-threatening Pulmonary Embolism

Embolectomy for acute pulmonary thromboembolism: From Trendelenburg’s procedure to the contemporary surgical approach

The effect of neutrophil/lymphocyte ratio on 1-year mortality in pulmonary embolism diagnosed patients

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