Massive increase in splenic germinal centre of chickens experimentally-infected with Trypanosoma brucei brucei

Joshua, R.A.

doi:10.1016/0304-4017(83)90068-7

Cited by 5 publications

(3 citation statements)

References 8 publications

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“…Chickens are naturally resistant to the 2016). Chickens are naturally resistant to the disease (JOSHUA, 1982). In humans, disease (JOSHUA, 1982).…”

Section: Introduction Introduction Preamble Preamblementioning

confidence: 99%

“…Chickens are naturally resistant to the disease (JOSHUA, 1982). In humans, disease (JOSHUA, 1982). In humans, T. brucei rhodesiense T. brucei rhodesiense is responsible for an acute is responsible for an acute form of trypanosomosis in Eastern and Southern Africa (FEVRE et al, 2005), while form of trypanosomosis in Eastern and Southern Africa (FEVRE et al, 2005), while T. T.…”

Section: Introduction Introduction Preamble Preamblementioning

confidence: 99%

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Chemotherapeutic control of trypanosomosis - a review of past measures, current status and future trends

Eghianruwa

Oridupa

2018

Vet. arhiv

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“…Chickens are naturally resistant to the 2016). Chickens are naturally resistant to the disease (JOSHUA, 1982). In humans, disease (JOSHUA, 1982).…”

Section: Introduction Introduction Preamble Preamblementioning

confidence: 99%

Section: Introduction Introduction Preamble Preamblementioning

confidence: 99%

Chemotherapeutic control of trypanosomosis - a review of past measures, current status and future trends

Eghianruwa

Oridupa

2018

Vet. arhiv

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“…In humans, Trypanosoma cruzi causes Chagas’ disease, which can cause serious heart dysfunction, and Trypanosoma brucei causes African sleeping sickness which affects about 300 000 persons each year (WHO report 1998). Trypanosomiasis is not as well studied in birds, but the parasite does affect the growth and fitness of highly infected individuals (for review see Joshua 1983; Molyneux et al . 1983; Apanius 1991).…”

Section: Introductionmentioning

confidence: 99%

Host specificity and incidence ofTrypanosomain some African rainforest birds: a molecular approach

2001

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Studies of host-parasite interactions in birds have contributed greatly to our understanding of the evolution and ecology of disease. Here we employ molecular techniques to determine the incidence and study the host-specificity of parasitic trypanosomes in the African avifauna. We developed a polymerase chain reaction (PCR)-based diagnostic test that amplified the small subunit ribosomal RNA gene (SSU rRNA) of Trypanosoma from avian blood samples. This nested PCR assay complements and corroborates information obtained by the traditional method of blood smear analysis. The test was used to describe the incidence of trypanosomes in 479 host individuals representing 71 rainforest bird species from Cameroon, the Ivory Coast and Equatorial Guinea. Forty-two (59%) of these potential host species harboured trypanosomes and 189 individuals (35%) were infected. To examine host and geographical specificity, we examined the morphology and sequenced a portion of the SSU rRNA gene from representative trypanosomes drawn from different hosts and collecting locations. In traditional blood smear analyses we identified two trypanosome morphospecies, T. avium and T. everetti. Our molecular and morphological results were congruent in that these two morphospecies had highly divergent SSU rRNA sequences, but the molecular assay also identified cryptic variation in T. avium, in which we found seven closely allied haplotypes. The pattern of sequence diversity within T. avium provides evidence for widespread trypanosome mixing across avian host taxa and across geographical locations. For example, T. avium lineages with identical haplotypes infected birds from different families, whereas single host species were infected by T. avium lineages with different haplotypes. Furthermore, some conspecific hosts from geographically distant sampling locations were infected with the same trypanosome lineage, but other individuals from those locations harboured different trypanosome lineages. This apparent lack of host or geographical specificity may have important consequences for the evolutionary and ecological interactions between parasitic trypanosomes and their avian hosts.

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PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2

Yang,

Wang,

Luo

et al. 2024

Molecular Therapy

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Massive increase in splenic germinal centre of chickens experimentally-infected with Trypanosoma brucei brucei

Cited by 5 publications

References 8 publications

Chemotherapeutic control of trypanosomosis - a review of past measures, current status and future trends

Chemotherapeutic control of trypanosomosis - a review of past measures, current status and future trends

Host specificity and incidence ofTrypanosomain some African rainforest birds: a molecular approach

PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2

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