Massive cutaneous complications due to snakebite: A case report and literature review

Sadeghi, Mahdieh; Barazandeh, Maryam; Zakariaei, Zakaria; Davoodi, Lotfollah; Tabaripour, Rabeeh; Fakhar, Mahdi; Zakariaei, Ashkan

doi:10.1002/ccr3.4129

Cited by 13 publications

(14 citation statements)

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“…Besides hematologic manifestations of snake bite, severe wound infections, such as cellulitis and necrotizing fasciitis have also been rarely reported 4,15 . The common signs and symptoms, such as erythema, in ammation, warmth, and local pain, may develop in the early to days 15 . With limb swelling, blisters and hemorrhagic bullae may develop in more severe cases, as happened with our patient 11 , Hemorrhagic blisters may occur at any bite location or even in dependent areas distant from the bite.…”

Section: Discussionmentioning

confidence: 99%

Echis carinatus snakebite, a rare case of fatal envenomation in a young Pakistani boy: a case report.

Siddiqui,

Siddiqui

2023

Preprint

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Snakebite poses a significant public health concern in the Sindh region of Pakistan,. The Echis carinatus,also known as Saw Scaled Viper (SSV), a venomous snake from the Viperidae family, is one of the species found in the area. It is responsible for a substantial number of the approximately 29,000 snakebites reported annually in the country. We reported the case of a young Pakistani boy, who was bitten by an SSV and developed venom-induced consumptive coagulopathy (VICC) within 24 hours. Additionally, he experienced necrotizing fasciitis at the bite site, which led to systemic septicemia and acute renal failure. Despite receiving the best treatment available, the patient passed away within five days. This case report underscores the importance of early FFP transfusions and prophylactic use of broad-spectrum antibiotics in treating VICC, acute renal failure, and wound infections.

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Section: Discussionmentioning

confidence: 99%

Echis carinatus snakebite, a rare case of fatal envenomation in a young Pakistani boy: a case report.

Siddiqui,

Siddiqui

2023

Preprint

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“…El mecanismo de formación de las flictenas permanece desconocido, pero se plantea que es generado por el efecto proteolítico del veneno en la unión dermoepidérmica. El veneno de la serpiente con efectos proteolíticos genera una extensa destrucción local que además predispone a la infección bacteriana por la flora oral de la serpiente (3,29,30). En cuanto al tratamiento de las mismas, existen diferentes posturas.…”

Section: Discussionunclassified

Mordeduras de ofidios en mano pediátrica y sus complicaciones locales

et al. 2022

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Mordeduras de ofidios en mano pediátrica y sus complicaciones localesMordidas de serpentes de mão pediátricas e suas complicações locais. Snake bites in pediatric hand and their local complications. RESUMENIntroducción: el envenenamiento por mordedura de ofidios es reconocido como un problema de salud pública según la Organización Mundial de la Salud. La baja incidencia sumada a la diversidad de presentaciones clínicas, edades, topografías afectadas, así como los diferentes protocolos en la bibliografía existente sobre algunos aspectos del tratamiento, hacen difícil el manejo sistematizado de estos pacientes. El objetivo de este trabajo es realizar una revisión sistemática de la literatura sobre mordedura de serpientes en pacientes pediátricos con afectación en mano y miembro superior, haciendo hincapié en la conducta frente las complicaciones loco-regionales. Por importancia y frecuencia destacamos al síndrome compartimental, las flictenas y las infecciones. Metodología: se realizó una búsqueda bibliográfica en MedLine/PubMed con las palabras clave: "Snake Bite hand Children" y "Snake Bite compartimental syndrome". Se incluyeron los artículos publicados en los últimos 10 años (2012 al 2022). Resultados: la búsqueda de artículos ante las palabras "Snake Bite hand Children" resultó en 20 articulos y la busqueda ante las palabras "Snake Bite compartimental syndrome" derivó en 34. Luego de aplicar los criterios de inclusión y exclusión se obtuvieron 30 artículos para el análisis. Conclusiones: la población pediátrica se encuentra más expuesta a las mordeduras por serpientes y a su vez a presentar lesiones más severas. El tratamiento del síndrome compartimental continúa siendo un tema de debate. El veneno inoculado puede simular un síndrome compartimental que puede revertir sin fasciotomías con el tratamiento adecuado. Igualmente, ante síntomas y signos claros de síndrome compartimental se sugiere realizar fasciotomías frente a las graves secuelas potenciales. Ante la aparición de flictenas, el destechado cuidadoso de la misma es un tratamiento adecuado. La mayoría de los autores coinciden con el tratamiento profiláctico con antibioticoterapia.

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“…Microbial (specifically bacterial) infections are a common secondary consequence of SBE, especially in viper bites, due to the extensive local tissue damage [ 8 , 9 ]. These infections can lead to serious complications such as exacerbating necrosis, systemic infections, and septic shock [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of Antibiotics in Managing Bacterial Infections on Bite Sites following Snakebite Envenomation

Salim

Almeida

Williams

et al. 2023

Toxins

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Snakebite envenomation (SBE) is a life-threatening medical emergency with a high mortality rate. Common secondary complications following SBE, such as wound infections, are significant due to their impact on worsening local tissue damage and causing systemic infection. Antivenoms are not effective to treat wound infections following SBE. Moreover, in several rural clinical settings, broad-spectrum antibiotics are often used without clear guidelines or based on limited laboratory data, resulting in undesirable side effects and exacerbated treatment costs. Therefore, robust antibiotic strategies should be developed to tackle this critical issue. Currently, there is limited information available on the bacterial profiles of SBE-induced infections and antibiotic susceptibility. Hence, it is essential to improve the knowledge of bacterial profiles and their antibiotic sensitivity in SBE victims to develop better treatment strategies. This study aimed to address this issue by examining the bacterial profiles of SBE victims with a specific focus on Russell’s viper envenomation. The most frequently found bacteria in the bites of SBE victims were Staphylococcus aureus, Klebsiella sp., Escherichia coli, and Pseudomonas aeruginosa. Linezolid, clindamycin, colistin, meropenem, and amikacin were some of the most effective antibiotics for commonly grown bacteria in SBE victims. Similarly, ciprofloxacin, ampicillin, amoxiclave, cefixime, and tetracyclin were the least effective antibiotics for common bacteria found in the wound swabs of SBE victims. These data provide robust guidance for infection management following SBE and offer useful insights to aid in designing effective treatment protocols for SBE with serious wound infections in rural areas where laboratory facilities may not be readily available.

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Massive cutaneous complications due to snakebite: A case report and literature review

Abstract: Wound infections due to snake bites such as cellulitis and necrotizing fasciitis, although not common, are seen in snake bites and if left untreated can cause serious complications.

Cited by 13 publications

References 14 publications

Echis carinatus snakebite, a rare case of fatal envenomation in a young Pakistani boy: a case report.

Echis carinatus snakebite, a rare case of fatal envenomation in a young Pakistani boy: a case report.

Mordeduras de ofidios en mano pediátrica y sus complicaciones locales

The Effectiveness of Antibiotics in Managing Bacterial Infections on Bite Sites following Snakebite Envenomation

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