Masses of nasal cavity, paranasal sinuses and nasopharynx: A clinicopathological study

Khan, Nafees A.; Zafar, Uzma; Afroz, Nishat; Ahmad, Shamshad; Hasan, Shirin

doi:10.1007/bf03050834

Cited by 33 publications

(22 citation statements)

References 12 publications

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“…Tobacco and air pollution have been implicated in the pathogenesis of SCC and these are very common in this part of the country. Khan et al have pointed out the high number of nasopharyngeal carcinomas in their study, but such cases were absent in our study [7].…”

Section: Figure 3: Inverted Papillomacontrasting

confidence: 73%

Clinicopathological Challenges in Tumors of the Nasal Cavity and Paranasal Sinuses: Our Experience

Kumari¹,

Pandey²,

Verma³

et al. 2022

Cureus

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Background and objectiveNasal and paranasal lesions are one of the most common otorhinolaryngological presentations encountered in clinical practice. Common presenting symptoms of these lesion range from nasal blockades, facial swellings, pain, nasal discharge, and epistaxis to orbital and ear symptoms. Diagnosis can be tricky as these symptoms are common in inflammatory conditions and tumors. The aim of our study was to observe the epidemiology and clinical pathological findings in patients with nasal and paranasal masses presenting to our institute and discuss the challenges in proper diagnosis and management due to similar presentations, and the role of histopathological examination (HPE) and immunohistochemistry (IHC) in overcoming these challenges.

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Section: Figure 3: Inverted Papillomacontrasting

confidence: 73%

Clinicopathological Challenges in Tumors of the Nasal Cavity and Paranasal Sinuses: Our Experience

Kumari¹,

Pandey²,

Verma³

et al. 2022

Cureus

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“…Almost similar to our findings, study of Boer CV, et al showed 0.12% NHL, Khan N, et al observed 2% NHL, and Parajuli S, et al found the incidence of lymphoma to be 3% in their study. 11,26,31 In contrast, Zhu L, et al showed 21.7% incidence of NHL. 32 NHL in the sinonasal and nasopharyngeal regions are uncommon and range from different B-cells and T-cells lymphomas to Natural Killer/T-cell lymphomas.…”

Section: Discussionmentioning

confidence: 94%

“…al confirmed NPC as the most common malignant lesion comprising 18.18% of the cases, whereas in the study of Khan N, et al it was the second most common malignancy comprising 4.16% of all lesions. 26,27 NPC is a malignancy with poor prognosis, and has a distinct geographical distribution and is mostly centered in east and southeast Asia. Dietary habits, lifestyle, and environmental exposures including role of Epstein Barr Virus (EBV) are the related factors.…”

Section: Discussionmentioning

confidence: 99%

“…Study of Khan N, et al showed presence of 3.12% SNUC in their study, whereas study of Parajuli S, et al didn't show a single case of SNUC. 11,26 SNUC is a malignancy with a propensity to metastasize, and usually presents at advanced stage leading to usually a poor prognosis with higher rates of recurrence. Despite advances in different modalities of treatment, the survival remains poor.…”

Section: Discussionmentioning

confidence: 99%

“…These malignant lesions are seen in a more or less similar fashion of incidence, or were absent throughout many studies. 2,3,5,10,11,26 Although these malignant lesions are not common, identification in histopathology is crucial for their proper management.…”

Section: Discussionmentioning

confidence: 99%

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Histopathology of Sinonasal and Nasopharyngeal Neoplastic Lesions in a Tertiary Care Center of Western Nepal: A Descriptive Cross-sectional Study

et al. 2021

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Introduction: Sinonasal and nasopharyngeal regions harbor diverse clinical conditions including many non-neoplastic and neoplastic lesions presenting with nasal obstruction, facial pain and swelling, rhinorrhea, epistaxis, and other oral, ear, and orbital symptoms. Histopathology of excised lesions is the mainstay for the definitive diagnosis and management of neoplastic lesions. The aim of this study is to find out the prevalence of neoplastic lesions among sinonasal and nasopharyngeal masses. Methods: This was a descriptive cross-sectional study conducted among sinonasal and nasopharyngeal masses in the Department of Pathology of a tertiary care center of western Nepal with primary data of 20 years from January 2001 to May 2020. Ethical approval was taken from the Institutional Review Committee. Convenience sampling method was used. Data management and statistical analysis were done using Statistical Package for Social Sciences. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage. Results: Out of 395 sinonasal and nasopharyngeal lesions, 134 (33.92%) (29.26-38.58 at 95% Confidence Interval) were neoplastic lesions. The malignant lesions were found to be 60 (44.77%). Inverted papilloma was the most common benign lesion comprising 28 (20.89%) of cases, and squamous cell carcinoma and nasopharyngeal carcinoma were the most common malignant lesions comprising 12 (8.95%) cases each. Conclusions: This study observed a variety of neoplastic lesions. The most common benign lesion was nasal polyp and squamous cell carcinoma and nasopharyngeal carcinoma were the most common malignant lesions.

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Sinonasal Mass—a Recent Study of Its Clinicopathological Profile

Agarwal

Panigrahi

2016

Indian J Surg Oncol

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A variety of non-neoplastic and neoplastic conditions involving the nasal cavity, paranasal sinuses (PNS), and nasopharynx are commonly encountered in clinical practice. The objectives of the study were to identify various pathological conditions that present with sinus or nasal mass, to understand their varied clinical behavior, to know the distribution of various lesions among the different age and sex groups, and to study the management of sinonasal masses and its outcome on follow-up. A prospective study was carried out from September 2013 to August 2015, in the Otorhinolaryngology Department of Hi-Tech Medical College & Hospital, Bhubaneswar, Odisha. The study included patients of any age and sex presenting with nasal symptoms (suspected of a sinonasal mass). This study included all cases seen during the above duration. Complete history was taken and full clinical examination was carried out. Majority of the patients with sinonasal masses were in the age group 41-50 years. Male:female ratio was about 1.2:1. Nasal obstruction was the most common presentation. Most common non-neoplastic lesion was rhinosporidosis and most common benign lesion was hemangioma. Most common malignant lesion was maxillary carcinoma. The presenting features of all sinonasal lesions may be indistinguishable and pose diagnostic dilemma. Correlation of clinical, radiologic, and most importantly pathologic modalities is of utmost importance for accurate diagnosis.

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Masses of nasal cavity, paranasal sinuses and nasopharynx: A clinicopathological study

Cited by 33 publications

References 12 publications

Clinicopathological Challenges in Tumors of the Nasal Cavity and Paranasal Sinuses: Our Experience

Clinicopathological Challenges in Tumors of the Nasal Cavity and Paranasal Sinuses: Our Experience

Histopathology of Sinonasal and Nasopharyngeal Neoplastic Lesions in a Tertiary Care Center of Western Nepal: A Descriptive Cross-sectional Study

Sinonasal Mass—a Recent Study of Its Clinicopathological Profile

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