Masses of myeloadipose tissue: Radiological and clinical considerations

Papavasiliou, C.; Γουλιάμος, Αθανάσιος; Deligiorgi, Eleni; Vlahos, Lambros; Cambouris, Theophanis

doi:10.1016/0360-3016(90)90023-d

Cited by 27 publications

(21 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…While end-stage, postmitotic cells, such as erythrocytes and granulocytes, are relatively radioresistant, mitotic cells (especially stem cells) arc highly radiosensitive. In the literature, the dose of radiation given to patients who present with spinal cord compression caused by extra medullary hematopoiesis has varied from 8.5 to 30 Gy [3][4][5][7][8][9]. While the range of radiation doses is large, much of the variability can be attributed to the size of the hematopoietic tissue mass and the radiation tolerance of surrounding normal tissues.…”

Section: Discussionmentioning

confidence: 99%

Combined Radiotherapeutic and Surgical Management of a Spinal Cord Compression by Extramedullary Hematopoiesis in a Patient with Hemoglobin E Beta-Thalassemia

et al. 1994

View full text Add to dashboard Cite

A 22-year-old male with a history of hemoglobin E β°-thalassemia presented with thoracic spinal cord compression due to extrameduUary hematopoietic tissue in the epidural space. Following decompressive laminectomy, this epidural mass was irradiated to 20.4 Gy in 12 fractions. The patient made a complete recovery from his neurological symptoms following treatment. Follow-up radiographs showed significant reductions in size of the extradural tumor. Results from this case supported by review of the literature suggest that radiation therapy, with or without decompressive surgery, is an effective therapy in treatment of patients with spinal cord compression due to epidural extrameduUary hematopoietic tissue.

show abstract

Section: Discussionmentioning

confidence: 99%

Combined Radiotherapeutic and Surgical Management of a Spinal Cord Compression by Extramedullary Hematopoiesis in a Patient with Hemoglobin E Beta-Thalassemia

et al. 1994

View full text Add to dashboard Cite

show abstract

“…Size of EAM ranges between 4 and 15 cm with a mean diameter of 8.2 cm [2]. Adrenal myelolipoma and EAM cause no specific symptoms [2,6,7]. In particular, no disorders of the peripheral blood or bone marrow were observed.…”

Section: Discussionmentioning

confidence: 90%

“…Imaging differential diagnosis of bilateral thoracic EAM includes primary or secondary tumors of lymph nodes, neurogenic tumors, and rarely paravertebral thoracic extramedullary hematopoiesis [1,7]. The inhomogeneuos contrast enhancement in CT scan may raise suspicions for a high grade lymphoma or lymph node metastasis of a malignant tumor.…”

Section: Discussionmentioning

confidence: 99%

Bilateral thoracic extraadrenal myelolipoma

Franiel

Fleischer

Raab

et al. 2004

European Journal of Cardio-Thoracic Surgery

View full text Add to dashboard Cite

Myelolipoma commonly occurs in the adrenal gland and is composed of both adipose tissue and normal hematopoietic elements. Extraadrenal myelolipoma may occur in the retroperitoneum, stomach, liver, lung, and in 3% of cases even in the mediastinum. We present a 65-year-old female patient with unspecific clinical symptoms. Routine chest roentgenograms revealed bilateral widening of the posterior mediastinum. Computed tomography showed bilateral, paravertebral lesions of 4.5 and 6.5 cm in diameter, respectively. After surgical removal, bilateral thoracic myelolipoma was pathomorphologically diagnosed. The imaging differential diagnosis of bilateral solid lesions in the posterior mediastinum including lymph node metastases, lymphomas, neurogenic tumors and extramedullary hematopoietic tumors is discussed.

show abstract

“…Paravertebrale Lokalisationen einer EMH können einen signalintensen Randsaum in T1-gewichteten Aufnahmen aufweisen, der Fettgewebe als möglichen Bestandteil einer EMH repräsentiert [29,31,35]. Auf T2-gewichteten Bildern zeigen EMH-Foci im Vergleich zum umgebenden Muskelgewebe eine höhere Signalintensität [8,19,29].…”

Section: Extramedullary Hematopoiesis In the Paravertebral Spaceunclassified

“…Die optimale Strahlendosis ist dabei nicht bekannt [19,24,31]. Strahlendosen ab 7,5 Gy können bereits zu einer kompletten Rückbildung von Symptomen führen [6,9], komplette Remissionen von entsprechenden Raumforderungen kön-nen dagegen auch höhere Gesamtdosen von 15-30 Gy erfordern [21,30].…”

Section: Extramedullary Hematopoiesis In the Paravertebral Spaceunclassified

Extramedulläre Blutbildung im paravertebralen Raum

Raab¹,

Simon²,

Schmidtberger³

et al. 2002

Medizinische Klinik

View full text Add to dashboard Cite

Clinical presentation, knowledge of the underlying disease and of imaging findings are essential in the diagnosis of extramedullary hematopoiesis. MRI is the imaging modality of choice in the primary diagnosis of extramedullary hematopoiesis. Possible extension of the disease into the intraspinal space can be evaluated with high accuracy and differential diagnosis can be facilitated. In addition, MRI is of use in the accurate planning of radiation fields as well as during follow-up of extramedullary hematopoiesis.

show abstract

Masses of myeloadipose tissue: Radiological and clinical considerations

Cited by 27 publications

References 39 publications

Combined Radiotherapeutic and Surgical Management of a Spinal Cord Compression by Extramedullary Hematopoiesis in a Patient with Hemoglobin E Beta-Thalassemia

Combined Radiotherapeutic and Surgical Management of a Spinal Cord Compression by Extramedullary Hematopoiesis in a Patient with Hemoglobin E Beta-Thalassemia

Bilateral thoracic extraadrenal myelolipoma

Extramedulläre Blutbildung im paravertebralen Raum

Contact Info

Product

Resources

About