Abstract:Drugs must satisfy several protocols and tests before
being approved
for the market. Among them, forced degradation studies aim to evaluate
drug stability under stressful conditions in order to predict the
formation of harmful degradation products (DPs). Recent advances in
LC–MS instrumentation have facilitated the structure elucidation
of degradants, although a comprehensive data analysis still represents
a bottle-neck due to the massive amount of data that can be easily
generated. MassChemSite has been recen… Show more
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