Mass Spectrometry: Overview and History

Comparison of gas chromatography detectors and its application in food analysis

“…Ion source is a device of MS that can allow ionization. There are many types of ion source in MS analysis, such as chemical ionization, thermal ionization and field ionization (Sparkman, 2000). In a mass analyzer, the ions are separated by their mass or charge ratio and after the ion being separated, the ion will be detected by an ion detector and the signal will be transferred to a data system.…”

Principles and Applications of LC-MS/MS for the Quantitative Bioanalysis of Analytes in Various Biological Samples

“…By various processes, ions of differing m/z values pass through the mass analyzer one at a time to reach the detector. When the ions strike the detector, they are converted into an electrical signal which, in turn, is converted into a digital response that can be stored by the computer (Sparkman, 2000). A mass specterometer does not directly determine mass but, determines the mass of a molecule by measuring the m/z of its ion.…”

Valproato de sódio referência versu genérico

“…O uso de Espectrômetro de Massas -Figura 3 -visa a mensuração quantitativa da massa de uma amostra, utilizando-se de metodologia para análise, a partir da ionização de classes químicas e sua separação iônica, a partir da relação massa sobre carga 128 . Com a técnica será obtida um esboço do sinal do iônico em detrimento de sua razão massa/carga, demonstrando a composição da amostra pela identificação e diferentes fragmentações 129 .…”