Mass spectrometry characterization, antioxidant activity, and cytotoxicity of the peel and pulp extracts of Pitomba

Exploring the Antioxidant Potential of Talisia esculenta Using In Vitro and In Vivo Approaches

“…The effects of T. esculenta extracts on the NIH/3T3 fibroblast cell line showed no cytotoxicity effects, which is an important characteristic for natural products in order to be considered for safe and viable application by the population [33,74]. The findings from our study are consistent with previous research conducted by [21], who also observed antioxidant effects in different cell lines. Additionally, the study by [75] with Litchi chinensis Sonn (Sapindaceae) supported our results.…”

“…De Souza et al [111] identified the presence of gallic acid, along with other compounds such as quinic acid, catechin, epicatechin, chlorogenic acid, caffeic acid, p-coumaric acid, ferulic acid, and quercetin in the T. esculenta extracts using HS-SPME/GC-MS and LC-MS/MS methods. Fraga et al [21] also identified rutin in T. esculenta fruit peel extracts. Similarly, the fruit peel from Dimocarpus longan (Sapindaceae) showed the presence of gallic acid, chlorogenic acid, corilagin, ferulic acid, ellagic acid, p-coumaric acid, quercetin, and kaempferol [112].…”

“…The DPPH assay showed that HF and IF had approximately 80% activity at the lowest evaluated concentration (50 µg/mL), and HC and IC had 50% of DPPH radical sequestration in a 50 µg/mL concentration and 90% at 250 µg/mL. Fraga et al [21] reported the antioxidant capacity of the ethanolic extract of T. esculenta fruit peels using six different antioxidant assays, achieving an 80% DPPH radical scavenging with an 80-fold concentration, which was used in the present study. Jantapaso and Mittraparp-Arthorn [70], evaluating aqueous extracts of fruit peels of Nephelium lappaceum L., another species of Sapindaceae, described an EC50 of 494.25 µg/mL for the DPPH assay, a value much higher than observed with T. esculenta.…”

“…Hil.) Raldk, commonly known as "pitombeira", is a native plant found in the Caatinga and Atlantic Forest biomes of Brazil [20,21]. Leaf infusions of T. esculenta have been traditionally employed in folk medicine as analgesics for back problems, rheumatism, and hypertension [22,23].…”

Determination of chemical composition, antioxidant activity, mass spectrometry and cytotoxicity of the Aiphanes aculeata palm fruit

“…When evaluating the extracts using ethanol and hexane solvents from the Talisia esculenta fruit pulp and peel using the L-929 cell line to evaluate the cytotoxic potential of the extracts, Fraga et al, (2021) determined that there is no cytotoxic potential at both tested concentrations (12.5 -200 µg/mL) in relation to the negative control, which are cells without any treatment, since there was no cell death, with cell viability above 70 %.…”