Mass Spectrometry: A Powerful Method for Monitoring Various Type of Leukemia, Especially MALDI-TOF in Leukemia’s Proteomics Studies Review

Ramandi, Negin Fasih; Faranoush, Mohammad; Ghassempour, Alireza; Aboul‐Enein, Hassan Y.

doi:10.1080/10408347.2021.1871844

Cited by 7 publications

(2 citation statements)

References 127 publications

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“…The TOF mass analyzer has the advantages of fast analysis speed and high upper limit of quality (Bolaños et al, 2003;Vestal, 2009). It is especially suitable for the analysis of large-throughput and fast analysis of biological macromolecules (Karas, 1990;Park et al, 2012;Ramandi et al, 2021). The TOF mass analyzer can measure the mass of many peptides simultaneously.…”

Section: Tof Mass Analyzermentioning

confidence: 99%

Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers

Li¹,

Chu²,

Tan³

et al. 2021

Front. Chem.

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Mass spectrometry (MS) is one of the most widely used analytical techniques in many fields. Recent developments in chemical and biological researches have drawn much attention to the measurement of substances with low abundances in samples. Continuous efforts have been made consequently to further improve the sensitivity of MS. Modifications on the mass analyzers of mass spectrometers offer a direct, universal and practical way to obtain higher sensitivity. This review provides a comprehensive overview of the latest developments in mass analyzers for the improvement of mass spectrometers’ sensitivity, including quadrupole, ion trap, time-of-flight (TOF) and Fourier transform ion cyclotron (FT-ICR), as well as different combinations of these mass analyzers. The advantages and limitations of different mass analyzers and their combinations are compared and discussed. This review provides guidance to the selection of suitable mass spectrometers in chemical and biological analytical applications. It is also beneficial to the development of novel mass spectrometers.

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Section: Tof Mass Analyzermentioning

confidence: 99%

Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers

Li¹,

Chu²,

Tan³

et al. 2021

Front. Chem.

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“… 4 , 5 , 6 Based on the clinical course of the disease and the cell of origin, there are four main types of leukemia, including acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), and chronic lymphocytic leukemia (CLL). 7 , 8 In addition, there is a rare set of atypical leukemia with different clinical features. 9 There are several treatment options for leukemia patients including radiation, 10 chemotherapy, 11 monoclonal antibodies, 12 and transplantation of hematopoietic stem cells.…”

Section: Introductionmentioning

confidence: 99%

Signaling pathways governing the behaviors of leukemia stem cells

Azizidoost¹,

Nasrolahi²,

Sheykhi-Sabzehpoush³

et al. 2024

Genes & Diseases

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Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Harvey

2024

Mass Spectrometry Reviews

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The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022. As with previous review, this review also includes a few papers that describe methods appropriate to analysis by MALDI, such as sample preparation, even though the ionization method is not MALDI. The review follows the same format as previous reviews. It is divided into three sections: (1) general aspects such as theory of the MALDI process, matrices, derivatization, MALDI imaging, fragmentation, quantification and the use of computer software for structural identification. (2) Applications to various structural types such as oligo‐ and polysaccharides, glycoproteins, glycolipids, glycosides and biopharmaceuticals, and (3) other general areas such as medicine, industrial processes, natural products and glycan synthesis where MALDI is extensively used. Much of the material relating to applications is presented in tabular form. MALDI is still an ideal technique for carbohydrate analysis, particularly in its ability to produce single ions from each analyte and advancements in the technique and range of applications show little sign of diminishing.

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Mass Spectrometry: A Powerful Method for Monitoring Various Type of Leukemia, Especially MALDI-TOF in Leukemia’s Proteomics Studies Review

Cited by 7 publications

References 127 publications

Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers

Towards Higher Sensitivity of Mass Spectrometry: A Perspective From the Mass Analyzers

Signaling pathways governing the behaviors of leukemia stem cells

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

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