Mass spectrometric behavior of phenolic acids standards and their analysis in the plant samples with LC/ESI/MS system

Ostrowski, Wojciech; Wojakowska, Anna; Grajzer, Magdalena; Stobiecki, Maciej

doi:10.1016/j.jchromb.2014.07.005

Cited by 26 publications

(25 citation statements)

References 28 publications

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“…The phenolic extracts of the oils dissolved in 50 ll of 98% methanol were analysed according to Ostrowski, Wojakowska, Grajzer, and Stobiecki (2014). Phenolic compounds were separated on a Poroshell 120 EC-C18 column; (Agilent, USA, 2.1 Â 100 mm, 2.7 lm) using a Waters Acquity UPLC system connected to a micrOToF-Q mass spectrometer (Bruker Daltonics).…”

Section: Identification and Quantificationmentioning

confidence: 99%

Characteristics of rose hip (Rosa canina L.) cold-pressed oil and its oxidative stability studied by the differential scanning calorimetry method

et al. 2015

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Section: Identification and Quantificationmentioning

confidence: 99%

Characteristics of rose hip (Rosa canina L.) cold-pressed oil and its oxidative stability studied by the differential scanning calorimetry method

et al. 2015

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“…In addition to these two simple phenolic acids, three other hydroxycinnamic acid derivatives 3 – 5 were detected: two in the hexane extract and one in the AcOEt extract of Cotula cinerea. The UV spectra of compounds 3 and 4 were characteristic of caffeic acid and coumaric acid, respectively . Their UPLC/QTOF‐MS spectra confirmed that these two compounds were caffeic and coumaric acid derivatives, while compound 5 was concluded to be a hydroxycinnamic acid derivative from its UV spectra …”

Section: Resultsmentioning

confidence: 92%

“…Five different phenolic acid compounds were found in the extracts of Cotula cinerea giving UV spectra characteristic of hydroxycinnamic acid derivatives . Among these, two were simple hydroxycinnamic derivatives, identified as caffeic acid ( 1 ) and coumaric acid ( 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…Among these, two were simple hydroxycinnamic derivatives, identified as caffeic acid ( 1 ) and coumaric acid ( 2 ). Their characterization was achieved by comparing their characteristic UV and MS spectral data with those of authentic standards (Table ) and previously reported data . In UHPLC/QTOF‐MS in negative ion mode, caffeic acid (3,4‐dihydroxycinnamic acid) gave a [M − H] − ion at m/z 179 (C 9 H 7 O 4 ).…”

Section: Resultsmentioning

confidence: 99%

“…In UHPLC/QTOF‐MS in negative ion mode, caffeic acid (3,4‐dihydroxycinnamic acid) gave a [M − H] − ion at m/z 179 (C 9 H 7 O 4 ). Another ion at m/z 135 corresponded to the loss of CO 2 from the carboxylate ion to form [M − H − CO 2 ] − …”

Section: Resultsmentioning

confidence: 99%

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Structural characterization of bioactive compounds in Cotula cinerea extracts by ultra‐high‐performance liquid chromatography with photodiode array and high‐resolution time‐of‐flight mass spectrometry detectors

Guaouguaou

Bebaha

Yadlapalli³

et al. 2020

Rapid Comm Mass Spectrometry

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Rationale Cotula cinerea of the Asteraceae family is a traditional Moroccan plant with various biological activities such as analgesic, cytotoxic and antioxidant effects which are often related to the presence of secondary metabolites. The present work aims to screen and identify the main phytochemicals compounds of Cotula cinerea extracts. Methods A method was developed that coupled a rapid and simple ultra‐high‐performance liquid chromatography system with both photodiode array and high‐resolution time‐of‐flight mass spectrometry detectors (UHPLC‐PDA/TOF‐HRMS) for the identification of the main secondary metabolites of three investigated extracts (hexane, AcOEt and n‐BuOH). Results A total of 30 phytocomponents pertaining to phenolic compounds and terpenoids have been detected, identified and quantified. Among these were previously reported free and conjugated coumaric and caffeic acids along with free and conjugated flavones and flavonols with kaempferol, quercetin, luteolin and apigenin aglycones. In addition, sulfated flavonoids were identified in the investigated extracts and are reported in this work for the first time in Cotula cinerea. The obtained results have been discussed in relation to the biological activities of the corresponding extracts. Conclusions This study proposed a practical strategy for rapidly screening and identifying secondary metabolites of Cotula cinerea and provided new information on the phytochemicals of this Saharan plant. This work has therefore provided useful results for further pharmacological studies and the design of new drugs based on this species and will facilitate the utilization of Cotula cinerea in the clinic and its safety evaluation. It is also hoped that the information presented here might stimulate further studies that will possibly lead to development of therapeutic agents from this plant.

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Comprehensive characterization of multiple components of Ziziphus jujuba Mill using UHPLC‐Q‐Exactive Orbitrap Mass Spectrometers

Qin

Fang

Shuai

et al. 2022

Food Science & Nutrition

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Ziziphus jujuba Mill is the dried ripe fruit of the Rhamnaceae family; it is widely distributed in Shandong, Henan, Liaoning, and other places in China. In folk medicine, it was used to restore vital energy, as a blood tonic, and for the treatment of spleen deficiency. To date, a complete investigation of the compounds of Z. jujuba has rarely been performed. Therefore, a reliable strategy based on UHPLC‐Q‐Exactive Orbitrap MS, combined with trace data acquisition mode (parallel reaction monitoring scanning, PRM) and multiple data processing methods, is necessary for the characterization of compounds in the Z. jujuba. Ultimately, 295 compounds, including 69 flavonoids, 60 alkaloids, 82 phenylpropanoids, 52 organic acids, and 32 other components, were identified in the Z. jujuba; of these, 270 have been reported in Z. jujuba for the first time. This study provides deep insights into the chemistry of Z. jujuba and could be useful for further studies aimed at identifying the factors contributing to the health benefits attributed to this fruit.

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Mass spectrometric behavior of phenolic acids standards and their analysis in the plant samples with LC/ESI/MS system

Cited by 26 publications

References 28 publications

Characteristics of rose hip (Rosa canina L.) cold-pressed oil and its oxidative stability studied by the differential scanning calorimetry method

Characteristics of rose hip (Rosa canina L.) cold-pressed oil and its oxidative stability studied by the differential scanning calorimetry method

Structural characterization of bioactive compounds in Cotula cinerea extracts by ultra‐high‐performance liquid chromatography with photodiode array and high‐resolution time‐of‐flight mass spectrometry detectors

Comprehensive characterization of multiple components of Ziziphus jujuba Mill using UHPLC‐Q‐Exactive Orbitrap Mass Spectrometers

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