“…Permethylation is therefore commonly performed prior to MALDI-MS of released N-or O-glycans, as it improves sensitivity, stabilizes the labile sialic-acid bonds, and enables the detection of non-sialylated and sialylated glycan species in positive-ion mode [8,20,21,29,30]. This approach was recently applied to characterize N-glycans from influenza antigen [31].…”