Mass Production of Source Core for Iodine-125 Seed

Lee, Jin Hee; Park, Ul Jae; Son, Kwang Jae; Choi, Kang Hyuk; Yu, Kook Hyun

doi:10.5012/bkcs.2014.35.7.2172

Cited by 2 publications

(1 citation statement)

References 14 publications

(6 reference statements)

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“…When a situation with two possible outcomes is present, it is interesting to evaluate electronegativity. For example, the paper by Lee et al [26] mixes pretreated silver rods with iodine-125, forming the core of a brachytherapy seed. Usually the radioactive iodine-125 solution is in the form of NaI 125 .…”

Section: Electronegativitymentioning

confidence: 99%

Start Here When Performing Radiochemical Reactions

Souza¹,

Kim²,

Hong³

2022

Radiopharmaceuticals - Current Research for Better Diagnosis and Therapy

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Radiation products are present in several fields of knowledge. From the energy field, with nuclear reactors and nuclear batteries, to the medical field, with nuclear medicine and radiation therapy (brachytherapy). Although chemistry works in the same way for radioactive and non-radioactive chemicals, an extra layer of problems is present in the radiochemical counter-part. Reactions can be unpredictable due to several factors. For example, iodine-125 in deposited in a silver wire to create the core of a medical radioactive seed. This core is the sealed forming a radioactive seed that are placed inside the cancer. Several aspects can be discussed in regards to radiation chemistry. For example: are there any competing ions? Each way my reaction is going? Each reaction is more likely to occur? Those are important questions, because, in the case of iodine, a volatile product can be formed causing contamination of laboratory, equipment, personal, and environment. This chapter attempts to create a guideline on how to safely proceed when a new radioactive chemical reaction. It discusses the steps by giving practical examples. The focus is in protecting the operator and the environment. The result can be achieved safely and be reliable contribution to science and society.

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Section: Electronegativitymentioning

confidence: 99%

Start Here When Performing Radiochemical Reactions

Souza¹,

Kim²,

Hong³

2022

Radiopharmaceuticals - Current Research for Better Diagnosis and Therapy

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Deposition of Iodine-125 on Silver Supports of Microsources for Prostate Cancer Brachytherapy

et al. 2022

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A method of iodine-125 deposition on a surface of microsource silver supports for brachytherapy of prostate cancer was reported, which includes preparing the support surface by sequentially treating them with nitric acid and thiourea solutions, followed by chlorination of the support surface with a chlorinating agent to form silver chloride on the support surface, and substitution of chlorine atoms for 125I atoms by placing supports containin silver chloride on the surface in a solution with 125I ions to create a 125I layer on the support surface. The method described allows fixing 125I on supports with a low activity distribution on each activity-carrying support.

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Mass Production of Source Core for Iodine-125 Seed

Cited by 2 publications

References 14 publications

Start Here When Performing Radiochemical Reactions

Start Here When Performing Radiochemical Reactions

Deposition of Iodine-125 on Silver Supports of Microsources for Prostate Cancer Brachytherapy

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