Abstract:Vascular congestion represents densely packed red blood cells (RBC) in the kidney circulation. In this study we tested the hypothesis that vascular congestion directly promotes tubular injury.
All studies were performed in male and female Wistar-Kyoto rats. Vascular congestion and tubular injury were histologically examined between renal venous clamping, renal arterial clamping and venous clamping of blood free kidneys. Vessels were occluded for either 15 or 45 minutes without reperfusion.
We found that veno… Show more
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