Masked hypertension

Aronow, Wilbert S.

doi:10.21037/atm.2017.09.24

Cited by 9 publications

(11 citation statements)

References 26 publications

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“…According to the latest US guidelines, adults with untreated office BP values consistently between 120/75 and 129/79 mm Hg are those who should be referred for out‐of‐office BP screening . Identification of MH is important because of the increased risk of cardiovascular disease and target organ damage that accompanies this form of hypertension …”

Section: Resultsmentioning

confidence: 99%

Expert panel consensus recommendations for ambulatory blood pressure monitoring in Asia: The HOPE Asia Network

Kario

Shin

Chen³

et al. 2019

J of Clinical Hypertension

115

167

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Hypertension is an important public health issue because of its association with a number of significant diseases and adverse outcomes. However, there are important ethnic differences in the pathogenesis and cardio-/cerebrovascular consequences of hypertension. Given the large populations and rapidly aging demographic in Asian regions, optimal strategies to diagnose and manage hypertension are of high importance. Ambulatory | 1251 KARIO et Al.

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Section: Resultsmentioning

confidence: 99%

Expert panel consensus recommendations for ambulatory blood pressure monitoring in Asia: The HOPE Asia Network

Kario

Shin

Chen³

et al. 2019

J of Clinical Hypertension

115

167

View full text Add to dashboard Cite

show abstract

“…5 Since most community residents lack routine health screening, most patients with MHT are not discovered until they develop symptoms caused by persistent hypertension, at which time there has already been significant cardiac structural remodeling and eventually irreversible decrease in left ventricular ejection fraction (LVEF). 6 Recently, assessment of global longitudinal strain (GLS) with the use of 2-dimensional speckle-tracking echocardiography technique has shown the ability to recognize minor injury in cardiac function before the decrease in LVEF. However, the association between MHT and impaired GLS has not yet been extensively discussed.…”

Section: Introductionmentioning

confidence: 99%

Relationship Between Masked Hypertension Measured by Ambulatory Blood Pressure Monitoring and Left Ventricular Global Longitudinal Strain: A Retrospective Study

Fu¹,

Hu²,

Sun³

et al. 2021

IJGM

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Masked hypertension (MHT), as an independent clinical entity, the cardiac dysfunction caused by it can be early detected through left ventricular global longitudinal strain (GLS), yet the quantitative relation between MHT and GLS is still unclear. Therefore, we tried to conduct a community-based retrospective study to define this relationship. Patients and Methods: A total of 308 enrolled participants from Dongguan, China, were divided into non-hypertension (NHT) and MHT groups. Baseline characteristics were recorded, and echocardiography and 24-hour ambulatory blood pressure monitoring were performed. Linear regression analysis and receiver-operating characteristic (ROC) curve analysis were used to assess the associations between MHT and GLS in univariate and multivariate models, and the dose-response curve was plotted to demonstrate their relationship. Results: The mean age of the NHT and MHT groups was 57 and 60 years, respectively. Signs of left ventricular diastolic function, E/A was reduced and E/e' was increased in the MHT group while those of the NHT group were nearly normal. The MHT group also showed a significantly lower ("worse") GLS than NHT (−15.2% vs −19.9%, P < 0.001) while left ventricular ejection fraction (LVEF) did not differ between the groups. Worse GLS was independently and significantly associated with MHT both in univariate (odds ratio [OR]: 1.97, P < 0.001) and stepwise multivariate regression analysis (OR: 1.99, P < 0.001). Comparison of ROC curve results showed that area under curve of GLS was larger than that of E/e' both in unadjusted (0.8673 vs 0.6831) and adjusted model (0.9178 vs 0.8284). Further analysis showed adjusted nonlinear correlation between MHT and GLS. Conclusion:Based on the relationship between MHT and GLS, in clinical practice, GLS measurement could facilitate diagnosis for suspected MHT patients and could define the extent of left ventricular dysfunction for diagnosed MHT patients.

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“…Since most community residents lack routine health screening, most patients with MHT are not discovered until they develop symptoms caused by persistent hypertension, at which time there has already been signi cant cardiac structural remodeling and eventually irreversible decrease in left ventricular ejection fraction (LVEF) [5]. Recently, assessment of global longitudinal strain (GLS) with the use of speckle-tracking echocardiography technique has shown the ability to recognize minor damage in cardiac function before the decrease in LVEF.…”

Section: Introductionmentioning

confidence: 99%

Relationship Between Masked Hypertension Measured by Ambulatory Blood Pressure Monitoring and Left Ventricular Global Longitudinal Strain

Fu¹,

Hu²,

Yi³

et al. 2021

Preprint

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Masked hypertension (MHT), as an independent clinical entity, its subclinical cardiac dysfunction can be early detected by left ventricular global longitudinal strain (GLS). Yet the relationship between MHT and GLS is still unclear. Therefore, we tried to conduct a community-based cross-sectional study to define this relationship. A total of 308 consecutively enrolled participants from Dongguan, China, were divided into non-hypertension (NHT) and MHT groups. Baseline characteristics were recorded, and 2-dimentional speckle-tracking echocardiography and 24-hour ambulatory blood pressure monitoring were performed. Univariate and multivariate linear regression analyses were used to assess the associations between MHT and GLS, and the dose–response curve was plotted to demonstrate their relationship. The mean age of the NHT and MHT groups was 57 and 59 years, respectively. Signs of left ventricular diastolic function, E/A (1.01 ± 0.26 vs 0.86 ± 0.23, P < 0.001) and E/e’ (8.58 ± 2.02 vs 11.70 ± 3.37, P < 0.001) were reduced in the MHT group while those of the NHT group were nearly normal. The MHT group also showed a significantly lower (‘worse’) GLS than NHT (-15.79% ± 2.81% vs -19.62% ± 1.67% vs , P < 0.001) while left ventricular ejection fraction (LVEF) did not differ between the groups. Worse GLS was independently and significantly associated with MHT both in univariate (odds ratio [OR]: 1.97, P < 0.001) and stepwise multivariate regression analysis (OR: 1.99, P < 0.001). Further analysis showed adjusted nonlinear correlation between MHT and GLS. Our study described the relationship between MHT and GLS and concluded that -14% of GLS as the cut-off value reflected MHT-associated myocardial injury before LVEF decreases.

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Masked hypertension

Cited by 9 publications

References 26 publications

Expert panel consensus recommendations for ambulatory blood pressure monitoring in Asia: The HOPE Asia Network

Expert panel consensus recommendations for ambulatory blood pressure monitoring in Asia: The HOPE Asia Network

Relationship Between Masked Hypertension Measured by Ambulatory Blood Pressure Monitoring and Left Ventricular Global Longitudinal Strain: A Retrospective Study

Relationship Between Masked Hypertension Measured by Ambulatory Blood Pressure Monitoring and Left Ventricular Global Longitudinal Strain

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