Masked comparison of silicone hydrogel lotrafilcon A and etafilcon A extended-wear bandage contact lenses after photorefractive keratectomy

Engle, Andrew T.; Laurent, John; Schallhorn, Steven C.; Toman, Steven D.; Newacheck, James S.; Tanzer, David J.; Tidwell, James L.

doi:10.1016/j.jcrs.2004.09.022

Cited by 64 publications

(47 citation statements)

References 5 publications

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“…Engle et al reported that corneal re-epithelialization after PRK was faster with less subjective complaints within the first 48 hours with lotrafilcon-A BCL compared to those with hydrogel BCL. 10 Our study identified that both groups using silicone hydrogel contact lenses had quickly completed re-epithelisation within the first 48 hours.…”

Section: 910mentioning

confidence: 76%

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Comparison of Two Different Bandage Contact Lens Types Used After Corneal Crosslinking

Halili¹,

Acar²,

Yenerel³

2015

Turkiye Klinikleri J Ophthalmol

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A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : To compare the efficiacy of two types of silicone hydrogel bandage contact lenses (BCLs) after corneal collagen crosslinking (CXL) in keratoconus patients. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : In this prospective study, 36 keratoconus patients received CXL in both eye. Each patient received a BCL composed of balafilcon A (Pure Vision; Bauch&Lomb) (14.0 diameter, 8.6 base curve) in 1 eye and lotrafilcon B (Air Optix Aqua; Ciba Vision) (14.2 diameter, 8.6 base curve) in the fellow eye. Patients were masked to the lens type in each eye. Postoperative medication regimen was the same with both eye. Epithelial defect size, contact lens debris, conjunctival and limbal hyperemia, reepithelization and responses to a subjective-comfort questionnaire were assessed postoperatively at 1, 3, and 5 days. A paired Student's t test and chi-square tests were used when appropriate. R Re es su ul lt ts s: : Seventy-two eyes of 36 keratoconus patients who underwent CXL were analyzed. There was no statistically significant difference in epithelial defect size, conjunctival or limbal hyperemia between the 2 lenses at any postoperative visit. Three days postoperatively, re-epithelization was complete in 77.8% of eyes (28 eyes) in the balafilcon A group and 83.3% of the eyes (30 eyes) in the lotrafilcon B group. Lens deposition and patient discomfort was significantly higher with the balafilcon A group 5 days postoperatively (p<0.01 for both comparisons). C Co on nc cl lu us si io on n: : There were no differences in corneal re-epithelization between the 2 types of BCLs (p>0.01). However, lens deposition and patient discomfort was higher with balafilcon A (p<0.01).K Ke ey y W Wo or rd ds s: : Contact lenses; keratoconus; riboflavin Ö ÖZ ZE ET T A Am ma aç ç: : Keratokonus hastalarında kornea kollajen kroslink (KKK) sonrası kullanılan iki farklı tip bandaj kontakt lensin etkinliğinin karşılaştırılması. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Bu prospektif çalışma ile KKK uygulanan 36 keratokonus hastası değerlendirildi. Hastaların bir gözüne balafilcon A içe-rikli bandaj kontakt lens (BKL) (Pure Vision; Bauch&Lomb) (14,0 çap, 8,6 temel eğri), diğer gözle-rine lotrafilcon B içerikli BKL (Air Optix Aqua; Ciba Vision) (14,2 çap, 8,6 temel eğri) önerildi. Hastaların her bir gözüne bu lens tiplerinden biri uygulandı. Ameliyat sonrası her iki göz için aynı medikal tedavi rejimleri uygulandı. Ameliyat sonrası 1.,3.,ve 5. günlerde epitel defektinin büyük-lüğü, kontakt lens debris, konjonktival ve limbal hiperemi, tekrar epitelizasyon ve subjektif konfor anketine cevaplar değerlendirildi. Sonuçların değerlendirilmesinde eşleştirilmiş Student t test ve ki-kare testi kullanıldı. B Bu ul lg gu ul la ar r: : KKK olan 36 keratokonus hastasının 72 gözü değerlendirildi. Ameliyat sonrası epitel defekt büyüklüğü, konjonktival ve limbal hiperemi açısından değerlendirildi-ğinde her iki kontakt lens arasında istatistiksel olarak anlamlı fark saptanmadı. Ameliyat son...

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Section: 910mentioning

confidence: 76%

“…Epithelial defect size was calculated by the equation A=π[(a+b)/4]², where the longest dimension of the defect was a and the shortest dimension of the defect was b. 10 While there was no epithelial defect observed, bandage contact lens was removed. Flourescein was instilled to confirm the absence of an epithelial defect.…”

Section: Surgical Techniquementioning

confidence: 99%

Comparison of Two Different Bandage Contact Lens Types Used After Corneal Crosslinking

Halili¹,

Acar²,

Yenerel³

2015

Turkiye Klinikleri J Ophthalmol

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“…The diameter of epithelial removal was the same in all patients. The post PK remaining epithelial defect size (A) was calculated similar to other researchers [17] using the equation of A= π [(a+b)/4] 2.…”

Section: Discussionmentioning

confidence: 99%

Epithelial Defect Induced Photorefractive Surgery: Comparison of Two Mechanical Epithelial Removal Techniques

Alishiri¹

2013

CMR

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Abstract:Purpose: To compare the epithelial defect size after epithelial removal by Weck-Cel sponge (Medtronic) spatula and blunt scalpel hockey blade. Method: This prospective study comprised 100 cases of PRK with mean age of 26±5 years (range, 19 to 45) performed at Bina Eye Specialist Hospital from January to march 2012. The size of epithelium removal was the same in all patients and it was 8.5 mm 2 . Each patienst's right eyes epithelium was removed by Weck spounge and it was removed by Haki spatula in the left eye. The residual epithelial defect size was measured in both eyes after 4 days from surgery. Result: Of 200 eyes that met the inclusion criteria, the mean preoperative spherical equivalent (SE) refractive error in right eyes was -2.6±1.5 (Range: -1 to -7 D) versus 2.6±1.4 (Range: -1 to -6.5D) in left eyes (P= 0.527 ). The mean epithelial defect size after 4 days in right eyes was 1.5+-0.77 and it was 1.46 +-0.77 in the left eyes (P = 0.623). Conclusion: This sudy showed that there is no difference between corneal epithelial defect size in two methods of PRK surgery after corneal epithelial removal .We consider both methods to be comparable in terms of efficacy and believe the choice of one method over the other rests on the surgeon's decision and experience.

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“…However, the CL market is anything but small, with approximately 140 million current CL wearers worldwide that could benefit from using this technology, should the need arise for therapeutic intervention [49,50]. In addition, many spectacle wearers who undergo refractive surgery are able to wear a bandage lens for a short period of time [14,17,18,51], demonstrating the potential shortterm success of a therapeutic lens to treat disease. The higher cost of using a drug-delivering CL compared to eye drops may also be a barrier, thus putting the onus on the prescribing practitioner to be an advocate of the technology such that the virtues of the treatment strategy can be appropriately communicated.…”

Section: Acceptance -Can It Reach Clinicians and Affect Clinical Pracmentioning

confidence: 99%

“…Several commercially available CLs, including Pure Vision (balafilcon A, Bausch+Lomb), Acuvue 2 (etafilcon A, Vistakon Inc.), Acuvue Oasys (senofilcon A, Vistakon Inc.), and Air Optix Night & Day (lotrafilcon A, Alcon) are FDA approved for use as bandage lenses [13][14][15][16][17][18][19]. In most cases, antibiotics and anti-inflammatory drugs are administered in conjunction with the CLs by adding the medication topically over the lens in situ [13,20].…”

Section: Introductionmentioning

confidence: 99%

Insights to Using Contact Lenses for Drug Delivery

Phan

Hui²,

Subbaraman³

et al. 2013

Innovative Approaches for the Complexity of Fibromyalgia

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Masked comparison of silicone hydrogel lotrafilcon A and etafilcon A extended-wear bandage contact lenses after photorefractive keratectomy

Abstract: The lotrafilcon A lens resulted in significantly faster corneal reepithelialization and reduced patient discomfort in most patients during the first 48 hours after PRK.

Cited by 64 publications

References 5 publications

Comparison of Two Different Bandage Contact Lens Types Used After Corneal Crosslinking

Comparison of Two Different Bandage Contact Lens Types Used After Corneal Crosslinking

Epithelial Defect Induced Photorefractive Surgery: Comparison of Two Mechanical Epithelial Removal Techniques

Insights to Using Contact Lenses for Drug Delivery

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