Masgutova Neurosensorimotor Reflex Integration (MNRI) as a New Form of Manual Neuromodulation Technique

The Impact of MNRI Therapy on the Levels of Neurotransmitters Associated with Inflammatory Processes

“…The MNRI method was initially developed in Russia in 1989 and further developed in Eastern Europe over the subsequent years. Several scientific studies and clinical observations have shown that this non-pharmacological treatment modality was significant positive results towards improvement in the neurological functioning in individuals with sensorimotor or reflex development deficits, behavior disorders, speech and language pathologies, and learning disabilities [54][55][56][57][58][59][60]. MNRI appeared in the USA in 1996 and has gradually been accepted by professionals in over 40 countries.…”

“…MNRI is a neuromodulation method as it facilitates the neurodevelopment in individuals with various neurological deficits and enables them to improve their reflex circuit functions-integration of their sensory and motor aspects, postural control, motor coordination, and physiological markers [57,58]. This neuroplasticity and skill development enable improved functioning, development, and learning [18,[54][55][56][57][58][59][60]. The MNRI therapy program is based on the theory that impaired reflex circuits can be reconstructed and re-integrated, which involves awakening the sensorimotor genetic memory in individuals even with severe diagnosis (such as CP and brain damage) [57,58].…”

“…The stimulation of reflex pathways is aimed at strengthening and stabilizing the traces of genetic sensory-motor memory and at the activation of the innate defense mechanisms through the body's neuroendocrine hormonal 'alarm' system (HPA axis) (hypothalamus-pituitary-adrenal gland stress response cycle activation) in times of stress or danger [20]. MNRI exercises stimulate innate neuro-regulatory mechanisms and enhance stress resiliency immune function [55,56,60]. Repatterning activates the extrapyramidal nervous system (peripheral nerves, spinal cord, brain stem, and diencephalon), which is responsible for targeting lower motor neurons in the spinal cord that are involved in reflexes, locomotion, complex movements, and postural control [59,62].…”

“…The MNRI method addresses the neuro-sensorimotor aspect of early sensory-motor patterns and reflexes to support sensory-motor integration and neurodevelopment in children and adults with neuro deficits and learning challenges: CP, TBI [57][58][59][60], ASD [55] Down syndrome [55,56,67,68], and other neurological disorders [69][70][71]. MNRI method meets the ever-increasing demands for neurorehabilitation of individuals with impaired sensorimotor functions due to central nervous system damage or dysfunction.…”

The Effect of the MNRI Method on Neurotransmitter Biomarkers of Individuals with Neurodevelopmental Disorders

“…Masgutova Neurosensorimotor Reflex Method (MNRI) addresses the neurosensorimotor aspect of early sensory-motor patterns and reflexes to support sensory-motor integration and neurodevelopment of children and adults with neurodeficits and learning challenges: CP, TBI [5] [6] [7] [8], ASD [9] [10] Down syndrome [11] [12] [13] [14] [15] and other [16] [17]. MNRI therapy meets the ever-increasing demands for neurorehabilitation of individuals with impaired sensorimotor functions due to damage or dysfunctions in central nervous systems.…”