MASCARA: coexpression analysis in data from designed experiments
Fred T.G. White,
Anna Heintz-Buschart,
Lemeng Dong
et al.
Abstract:Experiments in plant transcriptomics are usually designed to induce variation in a pathway of interest. Harsh experimental conditions can cause widespread transcriptional changes between groups. Discovering coexpression within a pathway of interest (here the strigolactone pathway) in this context is hampered by the dominant variance induced by the design. Minor changes in experimental conditions not controlled for may affect the plants, leading to small coordinated differences in genes within pathways of inter… Show more
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