If the leptoquarks proposed to account for the intriguing anomalies observed in the B-meson decays, R D ( * ) and R K ( * ) , as well as in the anomalous magnetic moment of the muon, (g − 2)µ, can be embedded into the scotogenic Dirac neutrino model, all these flavor anomalies, together with the origin of neutrino masses and the nature of dark matter, would be potentially addressed in a unified picture. Among the minimal seesaw, one-loop, and two-loop realizations of the dimension-4 effective operator L4 for the Dirac neutrino masses, we show that plenty of diagrams associated with the two-loop realizations of L4 can support the coexistence of leptoquarks and dark matter candidates. After a simple match of these leptoquarks to those that can accommodate all the flavor anomalies, we establish the scotogenic Dirac neutrino models embedded with leptoquarks, which could address all the problems mentioned above.