Marriage and outcomes of people with schizophrenia in rural China: 14-year follow-up study

Ran, Mao‐Sheng; Wong, Yin-Ling Irene; Yang, Shuyan; Ho, Petula Sik Ying; Mao, Wenjun; Li, Jie; Chan, Cecilia L. W.

doi:10.1016/j.schres.2016.10.034

Cited by 35 publications

(31 citation statements)

References 34 publications

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“…The effect of poor family attitudes on increasing rates of all-cause mortality and death due to other causes was unique for rural China, where family caregiving and support play a major role in patients’ treatment and care. 30 , 31 Evidence shows that having poorer familial attitudes towards persons with schizophrenia might be associated with living without family caregivers, poorer mental status, lower rates of remission, less access to antipsychotic medications and lower social functioning, 31 which in turn increase the risks of all-cause mortality and death by accidents and other causes. Evidence shows that socioeconomic development has shaped the treatment status of persons with schizophrenia in rural China.…”

Section: Discussionmentioning

confidence: 99%

Mortality and suicide in schizophrenia: 21-year follow-up in rural China

et al. 2020

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Background Little is known about the trend and predictors of 21-year mortality and suicide patterns in persons with schizophrenia. Aims To explore the trend and predictors of 21-year mortality and suicide in persons with schizophrenia in rural China. Method This longitudinal follow-up study included 510 persons with schizophrenia who were identified in a mental health survey of individuals (≥15 years old) in 1994 in six townships of Xinjin County, Chengdu, China, and followed up in three waves until 2015. Kaplan–Meier survival analysis and Cox hazard regressions were conducted. Results Of the 510 participants, 196 died (38.4% mortality) between 1994 and 2015; 13.8% of the deaths (n = 27) were due to suicide. Life expectancy was lower for men than for women (50.6 v. 58.5 years). Males consistently showed higher rates of mortality and suicide than females. Older participants had higher mortality (hazard ratio HR = 1.03, 95% CI 1.01–1.05) but lower suicide rates (HR = 0.95, 95% CI 0.93–0.98) than their younger counterparts. Poor family attitudes were associated with all-cause mortality and death due to other causes; no previous hospital admission and a history of suicide attempts independently predicted death by suicide. Conclusions Our findings suggest there is a high mortality and suicide rate in persons with schizophrenia in rural China, with different predictive factors for mortality and suicide. It is important to develop culture-specific, demographically tailored and community-based mental healthcare and to strengthen family intervention to improve the long-term outcome of persons with schizophrenia.

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Section: Discussionmentioning

confidence: 99%

Mortality and suicide in schizophrenia: 21-year follow-up in rural China

et al. 2020

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“…Men's premorbid characteristics, earlier onset, diagnosis, higher substance-use, and greater symptom severity could explain their poorer psychosocial outcomes and poorer academic attainment, functioning, accommodation conditions (Mancuso et al, 2014) and greater need for community management. Men were less likely to be married in this sample, unable to access the possibly protective effects of relationship found elsewhere (Ran et al, 2016) and this could potentially be associated with poorer psychosocial outcomes. Many difficulties could have preceded illness onset (Conrad et al, 2014); further analyses are underway, exploring antecedents and comorbidities.…”

Section: Sex Differences Alonementioning

confidence: 76%

“…However, in schizophrenia specifically, the prognosis for men is poorer than that for women (Ran et al, 2015), who have better remission, fewer relapses (Grossman et al, 2008), and better marital and housing outcomes (Olsson et al, 2016). While marriage may ameliorate the long-term effects of schizophrenia (Ran et al, 2016) men are relatively unlikely, compared to women with schizophrenia or the general population, to be (Campbell et al, 2012). Early intervention decreases mortality and morbidity (Henry et al, 2010;Mihalopoulos et al, 2009), encouraging community management (Gleeson et al, 2009;Jorm et al, 2008;Mihalopoulos et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Men and women with psychosis and the impact of illness-duration on sex-differences: The second Australian national survey of psychosis

Hanlon

Campbell

Single

et al. 2017

Psychiatry Research

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We aimed to examine and compare sex-differences in people receiving treatment for psychotic illnesses in community settings, based on long or short duration of illness; expecting association between longer illness-duration and worse outcomes in women and men. Clinical, demographic and service-use data from the Survey of High Impact Psychosis were analysed by sex and duration of illness (≤5 years; ≥6 years), using independent t-tests, chi-square tests, one-way ANOVA, and Cramer's V. Of the 1825 participants, 47% had schizophrenia, 17.5% bipolar and 16.1% schizo-affective disorders. More women than men had undertaken post-school education, maintained relationships, and been living in their own homes. Women with a shorter-illness-duration showed social functioning equivalent to non-ill women in the general population. Men tended to have an early illness onset, show premorbid dysfunction, be single, show severe disability, and to use illicit substances. Men with a longer-illness-duration were very socially disadvantaged and isolated, often experiencing homelessness and substance use. Men with a short-illness-duration were most likely to be in paid employment, but two-thirds earned less than $AUD500 per fortnight. Men with longer-illness-duration showed most disability, socially and globally. Interventions should be guided by diagnosis, but also by a person's sex and duration of illness.

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“…Compared with treated patients, those who were never treated were significantly older had significantly fewer family members, had higher rates of homelessness, being unmarried, living alone, being without a caregiver and poor family attitudes, including patient maltreatment. Ran's group has published a series of other papers dealing with various aspects of this 14‐year follow‐up …”

Section: Resultsmentioning

confidence: 99%

Very long-term outcome of schizophrenia

Volavka

Vevera

2018

Int J Clin Pract

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The long-term outcome of schizophrenia is highly variable, depending on access to mental healthcare, early detection of psychosis and pharmacological treatment. Recent data support the effectiveness of low-dose antipsychotic treatment for long-term maintenance in some patients. A proportion of first-episode schizophrenia patients, perhaps 20%, do not need long-term maintenance antipsychotic treatment. That proportion may be higher in schizophrenia spectrum patients. The reasons why these patients do not need the long-term treatment are not well understood. Methods to predict the membership in this subgroup are not yet good enough for clinical use in individual patients.

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Marriage and outcomes of people with schizophrenia in rural China: 14-year follow-up study

Cited by 35 publications

References 34 publications

Mortality and suicide in schizophrenia: 21-year follow-up in rural China

Mortality and suicide in schizophrenia: 21-year follow-up in rural China

Men and women with psychosis and the impact of illness-duration on sex-differences: The second Australian national survey of psychosis

Very long-term outcome of schizophrenia

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