2019
DOI: 10.1186/s12915-019-0684-y
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Abstract: Background Effective disease management depends on timely and accurate diagnosis to guide control measures. The capacity to distinguish between individuals in a pathogen population with specific properties such as fungicide resistance, toxin production and virulence profiles is often essential to inform disease management approaches. The genomics revolution has led to technologies that can rapidly produce high-resolution genotypic information to define individual variants of a pathogen species. Ho… Show more

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Cited by 43 publications
(57 citation statements)
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References 37 publications
(57 reference statements)
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“…Population genetic information drives the selection of isolates for activities as diverse as basic mechanistic research and plant germplasm screening for disease resistance. It also helps to pinpoint the origin of pandemic strains and the evolutionary potential of different pathogen populations [7][8][9][10][11][12]. A thorough understanding of the global population structure is essential for any surveillance program that aims at rapidly detecting pathogen incursions into new geographical areas.…”
Section: Introductionmentioning
confidence: 99%
“…Population genetic information drives the selection of isolates for activities as diverse as basic mechanistic research and plant germplasm screening for disease resistance. It also helps to pinpoint the origin of pandemic strains and the evolutionary potential of different pathogen populations [7][8][9][10][11][12]. A thorough understanding of the global population structure is essential for any surveillance program that aims at rapidly detecting pathogen incursions into new geographical areas.…”
Section: Introductionmentioning
confidence: 99%
“…Population genetic information drives the selection of isolates for activities as diverse as basic mechanistic research and plant germplasm screening for disease resistance. It also helps to pinpoint the origin of pandemic strains and the evolutionary potential of different pathogen populations [7][8][9][10][11][12] . A thorough understanding of the global population structure is essential for any surveillance program that aims at rapidly detecting pathogen incursions into new geographical areas.…”
Section: Introductionmentioning
confidence: 99%
“…Using this approach, they were able to identify respiratory pathogens in human samples. An alternative to sophisticated DNA extraction methodology is amplicon sequencing (Kilianski et al , 2015; Radhakrishnan et al , 2019). This latter approach was assessed in order to overcome the low throughput of the flowcells and to set up a more reliable and sensitive method, based on the amplification of two housekeeping genes followed by Nanopore sequencing.…”
Section: Discussionmentioning
confidence: 99%