Market surveillance: analysis of perfuming products for presence of allergens and prohibited substances

Ševčík, Václav; Andraščíková, Mária; Vavrouš, Adam; Moulisová, Alena; Vrbík, Karel; Bendová, Hana; Jírová, Dagmar; Kejlová, Kristína; Hložek, Tomáš

doi:10.1007/s11696-022-02225-w

Cited by 2 publications

(3 citation statements)

References 33 publications

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“…GC-MS is the most popular technique for fragrance analysis since they usually have low boiling points. Currently, GC is extensively used for sample infusion in EI-MS and has been greatly applied for the determination of allergens [ 28 , 31 , 98 , 107 , 144 , 145 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 165 , 166 ] and other risky components in cosmetic analysis ( Table A1 ). In addition to EI, other ionization techniques like chemical ionization (CI) and photoionization (PI) are employed for GC-MS investigations in this field.…”

Section: Ms Analysis Of Cosmetic Ingredientsmentioning

confidence: 99%

“… GC-MS and GC-MS/MS The method was tested in order to identify the presence of 24 regulated allergens and 21 prohibited substances in the cosmetic products: 2–17 allergens were identified per sample, and only safrole (of the prohibited substances) was present in a concentration > LOQ in 12 out of 166 tested samples. [ 144 ] 3 Six fragrance compositions. GC HR-MS and GC-LR-MS A total of 35 “difficult fragrance allergens” were quantified best by GC-orbitrap HR-MS. [ 145 ] 4 A “Lily” matrix—a combination of about 50 raw materials, mainly constituted of essential oils, aromatic plant extracts, synthetic ingredients, water and ethanol.…”

Section: Table A1mentioning

confidence: 99%

“…The method was tested in order to identify the presence of 24 regulated allergens and 21 prohibited substances in the cosmetic products: 2-17 allergens were identified per sample, and only safrole (of the prohibited substances) was present in a concentration > LOQ in 12 out of 166 tested samples. [144] 3…”

Section: Gc-ms and Gc-ms/msmentioning

confidence: 99%

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Mass-Spectrometry-Based Research of Cosmetic Ingredients

Serb,

Georgescu,

Onulov

et al. 2024

Molecules

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Cosmetic products are chemical substances or mixtures used on the skin, hair, nails, teeth, and the mucous membranes of the oral cavity, whose use is intended to clean, protect, correct body odor, perfume, keep in good condition, or change appearance. The analysis of cosmetic ingredients is often challenging because of their huge complexity and their adulteration. Among various analytical tools, mass spectrometry (MS) has been largely used for compound detection, ingredient screening, quality control, detection of product authenticity, and health risk evaluation. This work is focused on the MS applications in detecting and quantification of some common cosmetic ingredients, i.e., preservatives, dyes, heavy metals, allergens, and bioconjugates in various matrices (leave-on or rinse-off cosmetic products). As a global view, MS-based analysis of bioconjugates is a narrow field, and LC- and GC/GC×GC-MS are widely used for the investigation of preservatives, dyes, and fragrances, while inductively coupled plasma (ICP)-MS is ideal for comprehensive analysis of heavy metals. Ambient ionization approaches and advanced separation methods (i.e., convergence chromatography (UPC2)) coupled to MS have been proven to be an excellent choice for the analysis of scented allergens. At the same time, the current paper explores the challenges of MS-based analysis for cosmetic safety studies.

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