Marked increase in bone mineral density with oral phosphate and calcitriol in tumour-induced osteomalacia
Partha Pratim Chakraborty,
Rana Bhattacharjee,
Ajitesh Roy
et al.
Abstract:Patients with osteomalacia have a low bone mineral density (BMD) and are often misdiagnosed as osteoporosis. A marked increase in BMD is noticed following successful treatment of osteomalacia. The biochemical hallmark of tumour-induced osteomalacia (TIO) is hypophosphatemia. Patients with TIO often have severe hypophosphatemic osteomalacia and dual-energy X-ray absorptiometry may demonstrate low BMD. Surgical removal of the phosphatonin-secreting lesion restores serum phosphate, corrects osteomalacia and is as… Show more
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