Marked changes in right ventricular contractile pattern after cardiothoracic surgery: Implications for post-surgical assessment of right ventricular function

Raina, Amresh; Vaidya, Anjali; Gertz, Zachary M.; Chambers, Susan; Forfia, Paul R.

doi:10.1016/j.healun.2013.05.004

Cited by 165 publications

(131 citation statements)

References 19 publications

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“…Among functional indices at rest, RVFAC showed the best correlation to ventriculararterial coupling and contractile reserve, indicating that, if reliably measured, it could be a useful parameter for outcome or for screening. Our findings are in accordance with clinical results recently reported by RAINA et al [20]. They showed that RVFAC better reflects RV systolic function than TAPSE when the pericardium is kept open.…”

Section: Discussionsupporting

confidence: 94%

Right ventricular reserve in a piglet model of chronic pulmonary hypertension

et al. 2014

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Right ventricular (RV) response to exercise or pharmacological stress is not well documented in pulmonary hypertension (PH). We investigated the relationship between RV reserve and ventricular-arterial coupling.Surgical ligation of the left pulmonary artery was performed in 13 Large White piglets (PH group), thereafter weekly embolisations of the right lower lobe were performed for 5 weeks. A control group of six piglets underwent sham procedures. Right heart catheterisation and echocardiography were performed at week 6. Pressure-volume loops were recorded before and after dobutamine infusion.Induction of experimental PH resulted in a higher mean±SD pulmonary artery pressure (34±9 versus 14±2 mmHg; p<0.01) and in a lower ventricular-arterial coupling efficiency (0.66±0.18 versus 1.24±0.17; p<0.01) compared with controls at 6 weeks. Dobutamine-induced relative changes in RV stroke volume index (SVI) and end-systolic elastance were lower in the PH group (mean±SD 47±5% versus 20±5%, p<0.01, and 81±37% versus 32±14%, p<0.01, respectively). Change in SVI was strongly associated with resting ventricular-arterial coupling (R 2 =0.74; p<0.01). RV reserve was associated with ventricular-arterial coupling in a porcine model of chronic pressure overload. @ERSpublications Dobutamine testing in right ventricular pressure overload: a potentially useful method to assess contractile reserve

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Section: Discussionsupporting

confidence: 94%

Right ventricular reserve in a piglet model of chronic pulmonary hypertension

et al. 2014

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“…In addition, the echocardiographic parameters for assessment of RV dysfunction (2, 6) may be difficult to interpret after cardiothoracic surgery according to the results of previous studies showing postoperative disruption of the native RV contractile pattern (7,8). The reduction in the RV longitudinal contractile pattern has previously been described with several conventional echocardiographic indices (8), indicating that these observations are not related to a particular method of RV assessment but rather to a more fundamental change in the balance of longitudinal and contractile RV shortening after cardiac surgery (8). Speckle tracking-derived strain is a new modality for assessment of cardiac function (9).…”

Section: Introductionmentioning

confidence: 99%

Right Ventricular Performance After Valve Repair for Chronic Degenerative Mitral Regurgitation

Hyllén

Nozohoor

Ingvarsson

et al. 2014

The Annals of Thoracic Surgery

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Link to publication Citation for published version (APA): Hyllen, S., Nozohoor, S., Ingvarsson, A., Meurling, C., Wierup, P., & Sjögren, J. (2014). Right ventricular performance after valve repair for chronic degenerative mitral regurgitation. Annals of Thoracic Surgery, 98(6), 2023-2031. DOI: 10.1016/j.athoracsur.2014 General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research.• You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal Right Ventricular Performance Following Valve Repair for Chronic Degenerative Mitral Regurgitation

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“…Adopted and modified from Estep et al 65 *Note: based on observational data. The ''normal'' outflow graft peak velocities are not well defined.…”

Section: Hypertensive Emergencymentioning

confidence: 99%

“…56,63,64 However, recent data suggest that the correlation of TAPSE with overall RV systolic function may be weaker after cardiothoracic surgery and, therefore, this variable may have less clinical utility than the other measures. 65 Current data regarding the expected response of RV systolic function after LVAD implantation are conflicting: one study showed a significant improvement in RV FAC at 3 months, 55 but another study did not show a significant difference in this parameter at either 1 month or 6 months. 56 Valvular Assessment.…”

Section: Key Pointsmentioning

confidence: 99%