Marjolin's ulcer in a paraplegic man: A further example of the immunocompromised district

Marasca, Claudio; Annunziata, Maria Carmela; Cantelli, Mariateresa; Marasca, Dario; Fabbrocini, Gabriella

doi:10.1111/iwj.13022

Cited by 5 publications

(5 citation statements)

References 3 publications

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“…Epidermal injury following surgery strongly increases the release of proinflammatory cytokines resulting in the plugging of the follicle opening, follicle dilation, and the whole cascade of the development of new HS lesions [6,7]. The concept of an immunocompromised district, as already described for other diseases, could be also considered [8].…”

Section: Discussionmentioning

confidence: 99%

Development of New Lesions of Hidradenitis Suppurativa on a Caesarean Section Scar: A Manifestation of the Koebner Phenomenon?

Agiasofitou

Kanni

Platsidaki

et al. 2020

Skin Appendage Disord

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The Koebner phenomenon has been described following a surgical procedure in various dermatoses, including psoriasis, vitiligo, and lichen planus. • Koebnerization in hidradenitis suppurativa (HS) has recently been observed in patients in whom new lesions developed as a result of trauma. Novel Insights• The Koebner phenomenon following the scarring process on a cesarean section site has not previously been reported. • Avoidance of external trauma could be included in general measures of HS treatment. • Disease recurrence should be considered for patients treated with surgical excision of HS lesions. AbstractHidradenitis suppurativa (HS) is a chronic, inflammatory, recurrent skin disorder of the hair follicle. Trauma, mechanical pressure, or friction could have an important role in the pathogenesis of HS. We present a patient with HS who de-

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Section: Discussionmentioning

confidence: 99%

Development of New Lesions of Hidradenitis Suppurativa on a Caesarean Section Scar: A Manifestation of the Koebner Phenomenon?

Agiasofitou

Kanni

Platsidaki

et al. 2020

Skin Appendage Disord

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Section: Figurementioning

confidence: 99%

“…7 Chronic inflammation may lead to the development of an immunocompromised district, which is a skin area more vulnerable than the rest of the body for genetic or acquired reasons, prone to developing opportunistic infections, tumors, or dysimmune reactions. 8 Herein we report the case of a 46-year-old man showing a destructive lesion of upper lip, nasal cavity, and cleft palate. His medical history was positive for chronic cocaine abuse and plaque psoriasis not controlled by topical treatment.…”

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confidence: 99%

Neoadjuvant use of methotrexate in eosinophilic angiocentric fibrosis of upper lip and hard palate: A case report

Nastro

Ruggiero

Spanò

et al. 2021

Dermatologic Therapy

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“…5,6 In fact, local immune system is impaired by chronic lymphedema of any origin (eg, congenital or acquired), as immunocompetent cell (lymphocytes and Langerhans cells) trafficking is impeded. 7 This damage may trigger secondary angiogenesis with development of collateral hematic and lymphatic vessels and, eventually, vascular neoplasia. 7 Here, we report a rare case of PCDLBCL-LT without extracutaneous dissemination arising on a chronic unilateral lymphedema of the leg and we once again underline the importance of a prompt clinical and histological differential diagnosis of possible neoplasia in susceptible localization.…”

Section: F I G U R E 1 A-b Multiple and Confluent Nodules Arised On Hermentioning

confidence: 99%

A case of a primary cutaneous diffuse large B‐cell lymphoma, leg type

Marasca

Fabbrocini

Cinelli

et al. 2019

International Wound Journal

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A case of a primary cutaneous diffuse large B-cell lymphoma, leg type Dear Editors, An 82 year-old woman referred to our department for violaceous, multiple, and confluent nodules arised on her left leg 1 month before. The lesions were partially ulcerated and no clinical lymphadenopathy was noticed (Figure 1A,B). No symptoms, such as pain or burning sensations, were reported by the patient. She has been suffering from unilateral lymphedema of the left inferior limb, which occurred 1 year ago. Regarding her past medical history, she referred previous surgery for vulvar squamous cell carcinoma (2015), and she has been treated for heart failure with beta-blockers, angiotensin-converting enzyme-inhibitor, and diuretics. An incisional biopsy was planned in order to rule out malignancy. The histological examination with haematoxylin and eosin staining showed a diffuse proliferation of pleomorphic, medium to large lymphocytes in the deep dermis with mitosis, too. No alteration in the corresponding epidermis was noticed (Figure 2A-D). Immunohistochemistry was positive for CD20, Bcl-2, Bcl-6, and ki-67 (Figure 2E-H). All the results led to the diagnosis of a primary cutaneous

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Marjolin's ulcer in a paraplegic man: A further example of the immunocompromised district

Cited by 5 publications

References 3 publications

Development of New Lesions of Hidradenitis Suppurativa on a Caesarean Section Scar: A Manifestation of the Koebner Phenomenon?

Development of New Lesions of Hidradenitis Suppurativa on a Caesarean Section Scar: A Manifestation of the Koebner Phenomenon?

Neoadjuvant use of methotrexate in eosinophilic angiocentric fibrosis of upper lip and hard palate: A case report

A case of a primary cutaneous diffuse large B‐cell lymphoma, leg type

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