Marital dissolution and cognition: The mediating effect of β-amyloid neuropathology
Avinash Chandra,
Rifah Anjum,
Sheena Waters
et al.
Abstract:Background: Widowhood and divorce are extremely stressful life events and have been associated with high risk of dementia and cognitive impairment. However, the neurobiological mechanisms underlying how this risk is conferred requires further investigation. Alzheimer's disease (AD) pathology, such as β-amyloid (Aβ), may explain influences of chronic stress, such as those seen in disruptive marital transitions, on declines in cognition. Therefore, we examined whether Aβ mediates associations between marital dis… Show more
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