Marine peptides act as novel chemotherapeutic agent

Abstract

The marine environment represents a largely unexplored source of new microbes (bacteria, fungi, microalgae-cyanobacteria) that are potent producers of bioactive peptides. Here, we have discussed some novel peptides isolated from marine species exhibiting antibacterial, antifungal, antiviral, antiprotozoal activities. Therefore, marine peptides have attracted a great deal of attention due to their potential effects in promoting health and reducing disease. We have also discussed the extraction and commercial exploitation of peptides to become a possible future drug. Advancements in isolated techniques have allowed us easy access of less explored environment. Here, we summarize the future aim and scope of commercial application and production of microbial peptides from marine sources.

New Peptides from The Marine-Derived Fungi Aspergillus allahabadii and Aspergillus ochraceopetaliformis

“…As found from their counterparts from terrestrial environments, peptides are among the major groups of marine fungal natural products [5,6,7]. Considering the explosive progress in chemical investigation of marine fungi, demonstrated by the isolation of more than 3500 novel compounds, the potential of these organisms as the prolific sources of bioactive peptides is expected to continually increase [8,9,10,11,12,13]. Among the marine fungi, peptides and structurally-related compounds have mainly been isolated from the genera Acremonium , Aspergillus , Fusarium , and Penicillium [3].…”