Marine invasive macroalgae: Turning a real threat into a major opportunity - the biotechnological potential of Sargassum muticum and Asparagopsis armata

Pintéus, Susete; Lemos, Marco F.L.; Alves, Celso; Neugebauer, Agnieszka; Silva, Joana; Thomas, Olivier P.; Botana, Luís M.; Gaspar, Héléna; Pedrosa, Rui

doi:10.1016/j.algal.2018.06.018

Cited by 61 publications

(46 citation statements)

References 130 publications

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“…In the last decades, marine organisms, including seaweeds, have been targeted as potential sources of new active ingredients, distinct from the ones derived from terrestrial environments, with multiple health benefits [ 12 , 13 , 14 , 15 , 16 ]. Seaweeds have in their constitution several functional components, such as essential amino acids and proteins, carbohydrates, pigments, minerals, polysaccharides, dietary fibers, vitamins, polyunsaturated fatty acids, phenolics, and bioactive secondary metabolites, that have great potential to be used in innovative skincare formulations [ 10 , 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Highlighting the Biological Potential of the Brown Seaweed Fucus spiralis for Skin Applications

et al. 2020

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Skin aging is a biological process influenced by intrinsic and extrinsic factors. The last ones, mainly exposure to UV radiation, increases reactive oxygen species (ROS) production leading to a loss of extracellular matrix, also enhanced by enzymatic degradation of matrix supporting molecules. Thus, and with the growing demand for eco-friendly skin products, natural compounds extracted from brown seaweeds revealed to be good candidates due to their broad range of bioactivities, especially as antioxidants. The aim of this study was to assess the dermo-cosmetic potential of different fractions obtained from the brown seaweed Fucus spiralis. For this purpose, in vitro antioxidant (Total Phenolic Content (TPC), 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, Ferric Reducing Antioxidant Power (FRAP), Oxygen Radical Absorbance Capacity (ORAC)), anti-enzymatic (collagenase, elastase and hyaluronidase), antimicrobial, anti-inflammatory (NO production) and photoprotective (ROS production) capacities were evaluated. Although nearly all fractions evidenced antioxidant effects, fraction F10 demonstrated the highest antioxidant ability (EC50 of 38.5 µg/mL, DPPH assay), and exhibited a strong effect as an inhibitor of collagenase (0.037 µg/mL) and elastase (3.0 µg/mL). Moreover, this fraction was also the most potent on reducing ROS production promoted by H2O2 (IC50 of 41.3 µg/mL) and by UVB (IC50 of 31.3 µg/mL). These bioactivities can be attributed to its high content of phlorotannins, as evaluated by LC-MS analysis, reinforcing the potential of F. spiralis for further dermatological applications.

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Section: Introductionmentioning

confidence: 99%

Highlighting the Biological Potential of the Brown Seaweed Fucus spiralis for Skin Applications

et al. 2020

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“…This seaweed possesses chemical defence mechanisms that are nuclear to their invasiveness, based on the synthesis and storage of an array of secondary metabolites, which include over 100 halogenated compounds such as haloforms, haloacids, and haloketones (O. McConnell & Fenical, 1977). These halogenated volatile hydrocarbons containing one to four carbons are known antifeedant and cytotoxic compounds, among others (reviewed in Pinteus et al, 2018), and the pungent aroma of these algae is attributed to an essential oil that is composed mainly of bromoform with smaller amounts of other bromine, chlorine, and iodine-containing methane, ethane, ethanol, acetaldehydes, acetones, 2-acetoxypropanes, propenes, epoxypropanes, acroleins, and butenones, stored in vacuoles within gland cells (Burreson et al, 1976). These compounds potent biological effects can induce significant changes in terms of native community composition (Paul et al, 2006a) favoring A. armata in a given niche.…”

Section: Introductionmentioning

confidence: 99%

Impacts of The Invasive Seaweed <em>Asparagopsis armata</em> Exudate on Rockpool Invertebrates

Co¹,

Sc²,

Soares³

et al. 2020

Preprint

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The marine red algae Asparagopsis armata is an invasive species which competitive advantage arises from the production and release of large amounts of toxic compounds to the surrounding invaded area, reducing the abundance of native species. The main objective of this study was to evaluate the effects of this invasive seaweed on marine invertebrates by exposing the common prawn Palaemon elegans and the marine snail Gibbula umbilicalis to the exudate of this macroalgae. The seaweed was collected and placed in tanks, for 12 hours, in the dark in a 1:10 ratio. Afterwards the media containing its secondary metabolites was collected for further testing. Lethal and sublethal effects of A. armata were investigated. Biochemical biomarkers responses associated with energy metabolism (lactate dehydrogenase, LDH; electron transport system activity, ETS; content in lipids, proteins and carbohydrates) were analysed. The biomarker responses showed invertebrates’ physiological status impairment after exposure to low concentrations of this algae exudate. Highest concentrations of exudate significantly increased lipid content in both organisms. In the shrimp, protein content, ETS, and LDH were also significantly increased. On the contrary, these parameters were significantly decreased in G. umbilicalis. A behavioural impairment was also observed in G. umbilicalis exposed to A. armata exudate, with reduction in feeding consumption. These results represent an important step in the research of natural toxic exudates released to the environment and prospective effects of this seaweed in invaded communities under increasing global change scenarios.

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“…The coatings with Sargassum and Haliclona extracts can be good AF agents. Although there is no previous research where Sargassum or Halicona extracts have been incorporated in paint to evaluate their effectiveness in the field, different studies have referred to the genus Sargassum possessing excellent characteristics and compounds like palmitic acid that presented antifouling and non-cytotoxic properties [58] to be used in the formulation of antifouling materials, such as paints. Sponges of the genus Haliclona have been a good source of bioactive compounds, and some of these, like haliclona ciclamine A and halaminol A, have activity preventing fouling and colonisation, even inducing rapid larval settlement but preventing subsequent metamorphosis at precisely the same stage [48].…”

Section: Discussionmentioning

confidence: 99%

Biomimetic Approaches for the Development of New Antifouling Solutions: Study of Incorporation of Macroalgae and Sponge Extracts for the Development of New Environmentally-Friendly Coatings

Sánchez-Lozano

Hernández-Guerrero

Muñoz‐Ochoa

et al. 2019

IJMS

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Biofouling causes major economic losses in the maritime industry. In our site study, the Bay of La Paz (Gulf of California), biofouling on immersed structures is a major problem and is treated mostly with copper-based antifouling paints. Due to the known environmental effect of such treatments, the search for environmentally friendly alternatives in this zone of high biodiversity is a priority to ensure the conservation and protection of species. The aim of this work was to link chemical ecology to marine biotechnology: indeed, the natural defense of macroalgae and sponge was evaluated against biofoulers (biofilm and macrofoulers) from the same geographical zone, and some coatings formulation was done for field assays. Our approach combines in vitro and field bioassays to ensure the selection of the best AF agent prospects. The 1st step consisted of the selection of macroalgae (5 species) and sponges (2 species) with surfaces harboring a low level of colonizers; then extracts were prepared and assayed for toxicity against Artemia, activity towards key marine bacteria involved in biofilm formation in the Bay of La Paz, and the potency to inhibit adhesion of macroorganisms (phenoloxidase assays). The most active and non-toxic extracts were further studied for biofouling activity in the adhesion of the bacteria involved in biofilm formation and through incorporation in marine coatings which were immersed in La Paz Bay during 40 days. In vitro assays demonstrated that extracts of Laurencia gardneri, Sargassum horridum (macroalgae), Haliclona caerulea and Ircinia sp. (sponges) were the most promising. The field test results were of high interest as the best formulation were composed of extracts of H. caerulea and S. horridum and led to a reduction of 32% of biofouling compared with the control.

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Marine invasive macroalgae: Turning a real threat into a major opportunity - the biotechnological potential of Sargassum muticum and Asparagopsis armata

Cited by 61 publications

References 130 publications

Highlighting the Biological Potential of the Brown Seaweed Fucus spiralis for Skin Applications

Highlighting the Biological Potential of the Brown Seaweed Fucus spiralis for Skin Applications

Impacts of The Invasive Seaweed <em>Asparagopsis armata</em> Exudate on Rockpool Invertebrates

Biomimetic Approaches for the Development of New Antifouling Solutions: Study of Incorporation of Macroalgae and Sponge Extracts for the Development of New Environmentally-Friendly Coatings

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