Marine Algae-Derived Bioactive Peptides for Human Nutrition and Health

Abstract

Within the parent protein molecule, most peptides are inactive, and they are released with biofunctionalities after enzymatic hydrolysis. Marine algae have high protein content, up to 47% of the dry weight, depending on the season and the species. Recently, there is an increasing interest in using marine algae protein as a source of bioactive peptides due to their health promotion and disease therapy potentials. This review presents an overview of marine algae-derived bioactive peptides and especially highlights some key issues, such as in silico proteolysis and quantitative structure-activity relationship studies, in vivo fate of bioactive peptides, and novel technologies in bioactive peptides studies and production.

Algal Proteins: Extraction, Application, and Challenges Concerning Production

“…Bioactive peptides from algae have also been found to display bioactive properties, although they are not as well characterised compared to peptides from other sources (Table 2) [198]. Antimicrobial peptides have been identified from Saccharina longicruris protein hydrolysates, significantly decreasing the growth rate of Staphylococcus aureus [199].…”

Peptides, Peptidomimetics, and Polypeptides from Marine Sources: A Wealth of Natural Sources for Pharmaceutical Applications

“…For the isolation of antioxidant peptides from two different fishes, they treated fish skin suspension with pepsin for 2 h, after which trypsin and α-chymotrypsin were added for a further 2.5 h incubation [121]. The enzymatic hydrolysis process for the production of peptides from parent proteins turns out to be the best method, as it is comparatively inexpensive, gives higher and faster yields, and produces more clean output that fits the requirements of industrial production [122]. …”

Laminaria species and usefulness in obstetrics and gynecology

“…Several medical advantages of algae is confirmed [1][2][3][4][5][6][7][8][9][10][11]. Of several species, Laminaria species is a group of marine algae that is generally known as sea brown algae.…”