Marijuana Use and Potential Implications of Marijuana Legalization

Abstract

Most states in the United States have legalized medical and/or recreational cannabis in response to public demand. Trends in states adopting such legislation demonstrate an increasing prevalence of cannabis use coincident to decreasing perceptions of risk of harm from cannabis products. When providing anticipatory guidance, pediatricians should be prepared to address childhood unintentional ingestion management and prevention, adolescent problem use, and cannabis as an alternative therapy for seizure disorders and other conditions.

Optogenetic brain‐stimulation reward: A new procedure to re‐evaluate the rewarding versus aversive effects of cannabinoids in dopamine transporter‐Cre mice

“…Cannabis is the second most commonly used psychotropic substance, following alcohol 1,2 . Cannabis is also the most commonly used illicit substance in the United States 2 .…”

Impacto de la legalización del consumo recreativo del cannabis

“…Las tendencias en los estados que han legalizado el cannabis y han presentado una prevalencia creciente del consumo de cannabis, que al mismo tiempo ha coincidido con la disminución de la percepción de riesgo, deben poner en alerta a los pediatras y éstos deben estar preparados para abordar el manejo y la prevención de la ingestión de cannabis no intencional en la infancia, así como del uso problemático en los adolescentes (Grigsby et al, 2020).…”

“…-Aumente el consumo de alcohol, tabaco y otras drogas. En este sentido, diversos estudios previos han tratado de analizar por separado algunas de estas consecuencias en los estados en los que ya se ha legalizado el cannabis para cualquier uso (Chung et al, 2019;Grigsby, Hoffmann y Moss, 2020;Hall y Lynskey, 2020;Nazif-Muñoz et al, 2020;Steinemann et al, 2018), sin embargo, no se encuentran trabajos que aborden de forma global todas las consecuencias y posibles repercusiones en todos los países donde se ha legalizado.…”

The legalization of cannabinoid products and standardizing cannabis-drug development in the United States: a brief report

“…Here is a short list of often oversimplified-but-contentious issues surrounding cannabis: epidemiology of use (adolescents, children, and maternal); acute intoxication and effects on driving; pregnancy and breastfeeding; later childhood outcomes, from use, abuse, or exposure; social and racial context of cannabis policy; risk behavior in adolescence vs use; adolescent learning and mental health sequelae; potential medical uses in minors; and cannabis-use behaviors and cannabis-use disorders. 15 Current production and distribution of medical cannabinoid products, approved at the state level, requires neither clinical trials nor federal regulatory approval. 6 This undermines the rigorous approval process required of standardized, pharmaceutically available cannabinoid preparations.…”

“…It can surely be argued that it is unclear as to the early benefits of increasing access to regulated forms of cannabis, and perhaps these perceived benefits may be short lived. 10,15,16 On one hand, we have decades of cannabis policy and data of outcomes related to prohibition, with a gradual liberalization/decriminalization of medical and adult use. On the other hand, we are only just beginning to see the true impact of laws enacted over the last several years.…”