Marijuana Use Among Adults 50 Years or Older in the 21st Century

Lloyd, Shawnta L.; Striley, Catherine W.

doi:10.1177/2333721418781668

Cited by 89 publications

(62 citation statements)

References 62 publications

(145 reference statements)

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“…In the absence of clinical trial data for medical cannabis use, largely due to cannabis still being a Schedule I substance, epidemiological studies may be helpful in understanding how older adults are currently using medical cannabis. A number of epidemiological studies from national surveys examining patterns of cannabis use in older adults already exist 1,[15][16][17][18] -studies document a significant increase in cannabis use by older people over the past two decades, 1,17,18 with one study by Han and Palamar showing that among U.S. older adults age 65 + years, there was an increase in the use of cannabis from 2.4% in 2015 to 4.2% in 2018. 1 A number of reasons for these increases have been proposed, including changing attitudes of cannabis among older people, changes in the legal status in individual states, and unique health care needs of patients.…”

Section: Introductionmentioning

confidence: 99%

Patterns of Medical Cannabis Use Among Older Adults from a Cannabis Dispensary in New York State

Kaufmann

Kim

Miyoshi

et al. 2022

Cannabis and Cannabinoid Research

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Background: Cannabis use has increased among older adults. Few epidemiological studies have examined the medical diseases reported for cannabis use, routes of cannabis administration, and methods of consumption among older adults, and how they differ from younger adults. Methods: We analyzed invoice data on purchases of cannabis products from a large medical cannabis dispensary in New York State between January 1, 2016 and December 31, 2017. Data came from n = 11,590 patients stratified by ages 18-49 (n = 4,606), 50-64 (n = 3,993), and ‡ 65 years (n = 2,991). We assessed differences in groups by demographic characteristics of patients, qualifying conditions and symptoms for cannabis use, cannabis product dosing of THC and CBD, THC:CBD ratios, and cannabis delivery methods. Results: Among cannabis patients, 25.8% were aged ‡ 65 years, and 34.5% were ages 50-64. Across all age groups, severe or chronic pain was the predominant symptom for cannabis use, although older patients were more likely to use cannabis for cancer and Parkinson's disease among other conditions. Older adults were more likely to use sublingual tincture versus other consumption methods, to use products with a lower THC:CBD ratio, and to begin cannabis treatment with a lower THC and higher CBD dose compared with younger age groups. However, all age groups demonstrated a similar increase in THC dosing over time. Conclusion: Analysis of medical cannabis invoices from a dispensary in New York State showed that although there are similarities in patterns of cannabis use across all groups, there are key characteristics unique to the older adult medical cannabis user.

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Section: Introductionmentioning

confidence: 99%

Patterns of Medical Cannabis Use Among Older Adults from a Cannabis Dispensary in New York State

Kaufmann

Kim

Miyoshi

et al. 2022

Cannabis and Cannabinoid Research

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“…Other research has suggested that a higher frequency of cannabis use is significantly associated with an increased probability of reporting alcohol use disorder (Blazer and Wu 2009). This study, however, examined older adults (aged 50 or older) (Lloyd and Striley 2018), who have different characteristics than younger population. The current study found that, compared to those who reported no lifetime cannabis use, adolescents and youths with less frequent cannabis use (1-20 days/month) are more likely to report alcohol dependence and alcohol-associated adverse effects.…”

Section: Discussionmentioning

confidence: 96%

Frequency of cannabis use and alcohol-associated adverse effects in a representative sample of U.S. adolescents and youth (2002–2014) a cross-sectional study

et al. 2020

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Background While the link between frequent cannabis use and alcohol use disorders is well documented, it is not clear whether alcohol drinkers who use cannabis less frequently are also vulnerable to alcohol use disorders. We estimate the association of frequency of past 12-months cannabis use with alcohol-associated adverse effects variables in the same time frame: alcohol dependence, heavy drinking, driving under alcohol influence, alcohol-related interpersonal problems, use after interpersonal problems, alcohol-related risky behaviors, and alcohol-related legal problems. Methods We analyzed data from U.S. individuals aged 12 to 25 years who participated in annual, cross-sectional U.S. National Surveys on Drug Use and Health from 2002 to 2014. Logistic regression models were used to examine the association of cannabis use with six alcohol-associated adverse effects variables. Frequency of cannabis use served as the primary independent variable, and were divided into four categories: frequent use (21–30 days per month), less frequent use (1–20 days per month), no use over the past 12 months, and no lifetime cannabis use. Alcohol dependence and six alcohol-associated adverse effects variables served as our primary outcomes. Results The study included 465,090 respondents aged 12 to 25 years, among all past-year cannabis users, (47.5%) were less frequent (1–20 days/month) users. Less frequent cannabis use was highest among male, 15–25-year-olds, and non-Hispanic white 11.8, 84 and 10.6%, respectively. In adjusted models, past-year less frequent cannabis use (1–20 days/month) was significantly associated with past-year alcohol dependence (adjusted odds ratio aOR 5.57, 95% confidence interval (CI) 5.5–6.4); heavy drinking in the past-year (aOR 3.41, 95% CI 3.2–3.5); alcohol-related interpersonal problems in the past-year (aOR 7.33, 95% CI 7.0–7.5); use after interpersonal problems (aOR 5.17, 95% CI 4.8–5.5); alcohol-related risky behaviors (aOR 7.29, 95% CI 7.0–7.5), and, driving under influence of alcohol (aOR 7.19, 95% CI 6.9–7.4). No cannabis use past-year were more likely to report alcohol dependence (aOR 2.81, 95% CI 2.6–3) compared with no lifetime cannabis use. Conclusion These findings indicated that within the general population, not only frequent cannabis user (21–30 days per month) but even less frequent cannabis use (1–20 days/month) was significantly associated with past-year alcohol dependence and alcohol-associated adverse effects than no lifetime cannabis use. These adverse alcohol-related outcomes associated with less frequent cannabis use, should be taken under careful consideration in alcohol use disorder treatment setting and policy planning.

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“…Electronic cigarette (e-cigarette) and marijuana use has been increasing among cigarette smokers with or at risk for COPD 7,8 . The longterm impact of the consumption of such products is still being investigated.…”

Section: Exposuresmentioning

confidence: 99%

Insights into Chronic Obstructive Pulmonary Disease Epidemiology, Phenotypes and Outcomes from SPIROMICS

Labaki¹,

Martínez²,

Han³

2021

BRN

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SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS) is a multicentre National Institutes of Health funded cohort study of nearly 3000 never-smokers and ever-smokers (≥ 20 pack-years) with and without chronic obstructive pulmonary disease (COPD). It was designed to help fill gaps in our understanding of the biological complexity and clinical heterogeneity of COPD. The original goals for this study were to identify subgroups of smokers who may benefit from targeted therapies and to discover and validate intermediate biomarker endpoints. Here we review important findings from SPIROMICS over the past five years, including the impact of environmental and occupational exposures on the respiratory health of smokers, the characterisation of symptomatic smokers with preserved pulmonary function and the investigation of several diagnostic and prognostic biomarkers such as airway mucin concentration, functional small airways disease on chest computed tomography and a gene expression signature of interleukin 17A response in airway epithelium.

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Marijuana Use Among Adults 50 Years or Older in the 21st Century

Cited by 89 publications

References 62 publications

Patterns of Medical Cannabis Use Among Older Adults from a Cannabis Dispensary in New York State

Patterns of Medical Cannabis Use Among Older Adults from a Cannabis Dispensary in New York State

Frequency of cannabis use and alcohol-associated adverse effects in a representative sample of U.S. adolescents and youth (2002–2014) a cross-sectional study

Insights into Chronic Obstructive Pulmonary Disease Epidemiology, Phenotypes and Outcomes from SPIROMICS

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