Margaret Fuller was an American philosopher, writer, journalist and one of the first gender theorists. The article examines Fuller’s work and life in the context of 19th century American culture and social determinants influencing women’s lives. From a very early age, Fuller perceived her role in society different from the role designed for her as a biological girl by the cultural model of the times she lived in. The article focuses on Fuller’s achievements in the context of the self-made man/woman concept.