Maqui and Omega 3: effects on lipid profile,  oxidative stress levels and psycho-physical items in  human subjects

Cavezzi, Attilio; Corsi, Roberto; Dimitrova, Galya; Colucci, Roberto; Paccasassi, Stefania; Quinzi, Valentina; Fioroni, E; Campana, Fausto; Urso, S; Mosti, Giovanni

doi:10.15562/phytomedicine.2017.42

Cited by 3 publications

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“…In a recent publication 31 a direct action of Maqui 500® on parasympathetic and sympathetic systems was proven through HRV assessment 31 . This finding may partially explain the overall improvement of mental state after maqui intake, which is coherent with similar findings of other studies 20 where polyphenol supplementation proved to beneficially interfere with a few psychologic and neural patterns 32 .…”

Section: Discussionsupporting

confidence: 92%

“…Scientific literature documented that maqui berryderived nutraceuticals may improve a few biomarkers of cardiovascular diseases, inflammation and oxidative stress. Polyphenols and namely anthocyanins may have a role in CVD management [10][11][12][15][16][17][18][19][20][21][22] . The high delphinidin content and antioxidant power of maqui 13,14 may combat the venous disease-related free radical excess and inflammation.…”

Section: Discussionmentioning

confidence: 99%

“…Maqui-based food supplements have been tested with interesting results in oxidative stress and inflammation 15,16 ; similarly, a few studies have documented some maqui efficacy on cardiovascular/metabolic diseases [16][17][18][19][20][21] .…”

Section: Introductionmentioning

confidence: 99%

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Efficacy and safety of a Maqui berry-based nutraceutical in venous insufficiency of the lower limbs

Mici¹,

Prifti²,

Zikaj³

et al. 2022

JTAVR

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy and safety of a Maqui berry-based nutraceutical in venous insufficiency of the lower limbs

Mici¹,

Prifti²,

Zikaj³

et al. 2022

JTAVR

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Short-term effects of a maqui-based nutraceutical on heart rate variability, psycho-physical resilience and on a few metabolic biomarkers: a randomized controlled study

Cavezzi

Colucci

Bastiani

2022

Journal of Complementary and Integrative Medicine

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Objectives To assess the immediate/short-term outcomes of a maqui berry-based nutraceutical (MBN) supplementation on the autonomic nervous system (ANS), resilience level, metabolism and body composition. Patients and Methods A randomized controlled single-blind study was performed on healthy subjects. Throughout 30 days, one group took 1,000 mg/day of an MBN (Maqui 500®), the control group had no supplementation. On day 0 (T0) and 30 (T3) all subjects performed blood tests, bioimpedance spectroscopy and questionnaires for resilience, perceived stress and short-form 12 (SF12). At T0, 75′ after T0 (T1), on day 7 and at T3 the subjects underwent biometric parameter measurement and heart rate variability (HRV) test to investigate psycho-physical resilience. Results Fifteen subjects per group were included; abnormal seasonal high temperatures altered individuals’ lifestyle and nutrition, influencing the trial’s outcomes. Biometric parameters, blood pressure, oxygen saturation and blood tests did not differ between T0 and T3 in both groups. In the MBN group the HRV analysis showed a significant increase of ANS coordination (p=0.05), parasympathetic activity at 75′, very low frequencies and total power at T3, whereas these parameters decreased in the control group. SF12 mental score improved in the maqui group (p=0.02); the questionnaire-based outcomes showed no further variations. In the control subjects bioimpedance showed an increase of resistance and fat mass, with decreased total body water and lean mass (p=n.s.). Conclusions The maqui-based nutraceutical improved HRV, namely ANS activation/coordination, and SF12 mental component. Blood tests and bioimpedance/biometric parameters mildly varied. The elapsed hot weather likely biased many investigated variables.

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Heart Rate Variability

2018

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Background: Heart Rate Variability (HRV) is a parameter used to investigate the autonomous neural system (sympathetic and parasympathetic system). Reduced HRV is a risk factor which correlates with physical and psychological stress, psychoneuroendocrineimmunology dysregulation as well as with aging. HRV is considered a reliable parameter to investigate psycho-physical resilience, the latter being considered a key-factor for human longevity and the final target of hormesis pathways as well. Different chemical, physical, psychological stressors may interfere with HRV. Aims: The aim of our observational study was to assess the possible changes in HRV changes induced by a few targeted stimulations: breathing, maqui nutraceutical intake, physical activity and thermal stress, and maqui nutraceutical intake. Patients and Methods: An observational study was performed on 4 groups of subjects, for a total of 112 individuals, who underwent HRV analysis after administration of different stressors/stimuli, such as breathing, thermal stimulation, Maqui 500 ® nutraceutical intake and physical activity. The investigated parameters were: SDNN, RMSSD, MHRR, mean heart rate (MHR) and the three frequency-domain based bands (VLF, LF, HF). Results: Our outcomes demonstrate that HRV assessment is a useful and reliable investigation to highlight and monitor the effects of these stressors. Breathing was the stimulus which induced the most significant variation in HV parameters. Conclusions: Notwithstanding the short duration of the follow-up, immediate/short-term HRV assessment showed statistically significant variations of the main parameters (e.g. SDNN, RMSSD and frequency bands) in a few cases after stimuli exposure. Studies including larger cohorts and longer follow-up are needed and justified to corroborate our outcomes furthermore.

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Maqui and Omega 3: effects on lipid profile, oxidative stress levels and psycho-physical items in human subjects

Cited by 3 publications

References 0 publications

Efficacy and safety of a Maqui berry-based nutraceutical in venous insufficiency of the lower limbs

Efficacy and safety of a Maqui berry-based nutraceutical in venous insufficiency of the lower limbs

Short-term effects of a maqui-based nutraceutical on heart rate variability, psycho-physical resilience and on a few metabolic biomarkers: a randomized controlled study

Heart Rate Variability

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