Mapping the Onset of Psychosis: The Comprehensive Assessment of At-Risk Mental States

Yung, Alison R.; Yuen, Hok Pan; McGorry, Patrick; Phillips, Lisa; Kelly, Daniel P.; Dell'Olio, Margaret; Francey, Shona; Cosgrave, Elizabeth; Killackey, Eóin; Stanford, Carrie; Godfrey, Katherine; Buckby, Joe

doi:10.1080/j.1440-1614.2005.01714.x

Cited by 1,765 publications

(1,474 citation statements)

References 16 publications

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“…The catchment area includes the boroughs served by South London and Maudsley NHS Foundation Trust. UHR individuals were assessed by the OASIS service using the Comprehensive Assessment of AtRisk Mental States (CAARMS) assessment tool (Yung et al, 2005) Conferral of an at-risk status was established by two experienced clinicians and a consensus meeting of the OASIS clinical team.…”

Section: Participantsmentioning

confidence: 99%

Bullying victimisation and paranoid ideation in people at ultra high risk for psychosis

Valmaggia

Day

Kroll

et al. 2015

Schizophrenia Research

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Section: Participantsmentioning

confidence: 99%

Bullying victimisation and paranoid ideation in people at ultra high risk for psychosis

Valmaggia

Day

Kroll

et al. 2015

Schizophrenia Research

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“…Scheduled Interview for Prodromal Symptoms/Scale of Prodromal Symptoms (SIPS/ SOPS) Miller et al 2003], in an attempt to better predict the onset of psychosis. At PACE, the Comprehensive Assessment of At-Risk Mental States (CAARMS; Yung et al 2005) is used to rate the UHR status of young people at the age of peak risk for psychosis based on the criteria of: (1) attenuated psychotic symptoms; (2) brief limited intermittent psychotic symptoms (BLIPS); and/or (3) trait vulnerability for psychotic illness (schizotypal personality disorder or a history of psychosis in a first-degree relative), and deterioration in functioning or chronic low functioning.…”

mentioning

confidence: 99%

‘At-risk’ for psychosis research: where are we heading?

Lin

Nelson

Yung

2012

Epidemiol Psychiatr Sci

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The 'at-risk' criteria are a useful paradigm for investigating the psychological, neurocognitive, neurobiological and genetic risk factors for psychosis, specifically schizophrenia. To date, the primary outcome of interest in at-risk research has been the development of psychotic disorder, whereby patients are categorized as either having 'transitioned' or 'not transitioned'. Despite the acceptance of this dichotomy, it is important to consider that the threshold at which psychotic symptoms progress from attenuated to frank 'psychotic disorder' is arbitrary and may be incorrect or meaningless in terms of neurobiological and functional changes associated with psychosis. This has implications for clinical care and the search for markers of schizophrenia. We present recent research suggesting that the term 'outcome' needs to be broadened to incorporate non-psychotic diagnoses, functioning and negative symptoms. Shifting the traditional notion of outcome is the future challenge for at-risk research, but the inclusion of outcomes other than psychosis is likely to result in better aetiological models of psychotic illness.

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“…The past twenty years have seen increasingly rapid advances in the field of early intervention [1][2][3] ; not only due to the relevance of the issue but also because studies showed its positive impact and cost-effectiveness 4,5 . Early intervention aims to investigate early stages of psychosis also known as prodromal phase.…”

Section: Introductionmentioning

confidence: 99%

“…UHR are individuals at risk to develop psychosis who present the following symptoms at least two weeks most of the days: suspiciousness, perceptual distortions, poor or decline functioning, social withdrawal, hallucinations, disorganized thinking/speech, ideas of reference, depression, anxiety, sleep disturbance, difficulties in concentration that might indicate a risk of conversion to psychosis 1,3,6 and cognitive impairments 7,8 .…”

Section: Introductionmentioning

confidence: 99%

“…The SIPS 9 and the Comprehensive Assessment of At Risk Mental States (CAARMS) 11 are frequently used to classify individuals at UHR for academic purposes in specialized research centers, even though the UHR diagnosis remains clinical. The SIPS and the CAARMS are golden standard interview-based instruments conducted by experts, able to classify the experiences reported by the potential UHR individuals 12 ; but require long staff training and time, and can result on patient burden 10,12 .…”

Section: Introductionmentioning

confidence: 99%

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Prodromal Questionnaire: translation, adaptation to Portuguese and preliminary results in ultra-high risk individuals and first episode psychosis

Gonçalves

Martins

Gordon

et al. 2012

J. bras. psiquiatr.

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Objective: The Prodromal Questionnaire (PQ) is a 92-item self-report screening tool for individuals at ultra-high risk (UHR) to develop psychosis. This study aims to present the translation to Portuguese and preliminary results in UHR and first episode (FE) psychosis in a Portuguese sample. Methods: The PQ was translated from English to Portuguese by two bilingual researchers from the research program on early psychosis of the Instituto de Psiquiatria HCFMUSP, São Paulo, Brazil (ASAS -"Evaluation and Follow up of Adolescents and Young Adults in São Paulo") and back translated by two other researchers. The study participants (n = 11 ) were evaluated through the Portuguese version of the Prodromal Questionnaire (PQ) and SIPS. Results: The individuals at UHR (n = 7) presented a lower score than first episode patients (n = 4). The UHR mean scores and standard deviation on Portuguese version of the PQ were: 13.0 ± 10.0 points on positive symptoms subscale, and FE patients: 33.0 ± 10.0. Conclusion: The UHR and FE patients' of this study presented PQ scores similar to the ones found in the literature; what suggests that it is possible to use the PQ in Brazilian help-seeking individuals as a screening tool. RESUMOObjetivo: O Questionário Prodromal (PQ) é um instrumento de triagem e autorrelato com 92 itens para indivíduos com ultra-alto risco (UHR) para desenvolver psicose. Este estudo tem como objetivo apresentar a tradução desse questionário para português e seus resultados preliminares em uma amostra brasileira de UHR e primeiro episódio (FE) psicótico. Métodos: O PQ foi traduzido do inglês para o português por dois pesquisadores bilíngues do programa de pesquisa sobre psicose precoce do Instituto de Psiquiatria HCFMUSP, São Paulo, Brasil (ASAS "Avaliação e Acompanhamento de Adolescentes e Jovens Adultos em São Paulo") e retrotraduzido por dois outros pesquisadores. Os participantes (n = 11) do estudo foram avaliados por meio da versão em português do Questionário de Prodromal (PQ) e SIPS. Resultados: Os indivíduos com UHR (n = 7) apresentaram menor pontuação do que os pacientes de primeiro episódio (n = 4). Os escores médios e desvio-padrão dos Palavras-chave Ultra-alto risco, primeiro episódio psicótico, instrumento de rastreio.

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Mapping the Onset of Psychosis: The Comprehensive Assessment of At-Risk Mental States

Cited by 1,765 publications

References 16 publications

Bullying victimisation and paranoid ideation in people at ultra high risk for psychosis

Bullying victimisation and paranoid ideation in people at ultra high risk for psychosis

‘At-risk’ for psychosis research: where are we heading?

Prodromal Questionnaire: translation, adaptation to Portuguese and preliminary results in ultra-high risk individuals and first episode psychosis

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