Mapping research in assisted reproduction worldwide

García, Désirée; Massucci, Francesco Alessandro; Mosca, Alessandro; Ràfols, Ismael; Rodríguez, Amelia; Vassena, Rita

doi:10.1016/j.rbmo.2019.10.013

Cited by 7 publications

(12 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…New avenues of research should be promoted, such as the role of gut microbiota in the association between maternal factors and child health [103] as well as increased arterial stiffness in women, as recently reported [104]. Novel treatment for sexual dysfunction, new contraceptive agents, assisted reproduction [105], and strategies for preventing pregnancy complications should be tested in randomized clinical trials, with the ultimate aim to improve reproductive health.…”

Section: Discussionmentioning

confidence: 96%

Hypertension and Reproduction

et al. 2020

View full text Add to dashboard Cite

Purpose of Review Many aspects of reproduction have been associated with increased blood pressure and impaired glucose metabolism that reveals a subsequent increased risk of cardiovascular disease. The aim of this review is to assess reproductive life factors associated with an increased risk of hypertension and cardiovascular disease, e.g., early life programming, sexual, and reproductive health in men and women. Recent Findings Impaired fetal growth, with low birth weight adjusted for gestational age, has been found associated with hypertension in adulthood. Erectile dysfunction, currently considered an early diagnostic marker of cardiovascular disease preceding the manifestation of coronary artery disease by several years, frequently coexisting with hypertension, could also be exacerbated by some antihypertensive drugs. Male hypogonadism or subfertility are associated with increased cardiovascular risk. Hypertensive disorders in pregnancy including preeclampsia represent a major cause of maternal, fetal and neonatal morbidity, and mortality. The risk of developing preeclampsia can be substantially reduced in women at its high or moderate risk with a low dose of acetylsalicylic acid initiated from 12 weeks of gestation. An increased risk of hypertension in women following invasive-assisted reproductive technologies has been newly observed. Blood pressure elevation has been noticed following contraceptive pill use, around the menopause and in postmenopausal age. Furthermore, drug treatment of hypertension has to be considered as a factor with a potential impact on reproduction (e.g., due to teratogenic drug effects). Summary In summary, a deeper understanding of reproductive life effects on hypertension and metabolic abnormalities may improve prediction of future cardiovascular disease.

show abstract

Section: Discussionmentioning

confidence: 96%

Hypertension and Reproduction

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In the last two decades, ART practices around the world have increased considerably [ 1 – 4 ]. At the same time, with the global growth in academic publications [ 5 , 6 ], the volume of research output about both technical and non-technical aspects of ART has expanded substantially [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

“…Hence, the ELSI literature in ART reviewed in this paper, similarly to ELSI literature in general, is largely shaped by socio-cultural contexts, including economic, religious, and social norms, among other value-based factors, that significantly differ across various societies and circumstances [ 16 , 17 ]. Since this literature is largely concentrated in a limited number of countries or centers ([ 7 ]; Alon et al, 2023 — under review in JARG ), it may result in findings that are not globally representative or comprehensive. Hence, value-based perceptions from a few countries may shape the framing of and approach towards research questions and analysis worldwide, which may pose a challenge to be addressed.…”

Section: Introductionmentioning

confidence: 99%

Mapping international research output within ethical, legal, and social implications (ELSI) of assisted reproductive technologies

Alón

Chebance

Massucci³

et al. 2023

J Assist Reprod Genet

Self Cite

View full text Add to dashboard Cite

Purpose Research about ethical, legal, and social implications (ELSI) of assisted reproductive technologies (ART) is influenced by cultural and value-based perspectives. It impacts regulations, funding, and clinical practice, and shapes the perception of ART in society. We analyze trends in the global literature on ELSI of ART between 1999 and 2019. As most output is produced by North America, Western Europe, and Australia, we focus on international research, i.e., academic articles studying a different country than that of the corresponding author. Methods The corpus, extracted from PubMed, Web of Science, and Scopus, includes 7714 articles, of which 1260 involved international research. Analysis is based on titles, abstracts and keywords, classification into ART fields and Topic Modeling, the countries of corresponding author, and countries mentioned in abstracts. Results An absolute increase in the number of international studies, and their relative proportion. Trends of decentralization are apparent, yet geographic centralization remains, which reflects an unequal distribution of research funds across countries and may result in findings that do not reflect global diversity of norms and values. Preference for studying conceptual challenges through philosophical analysis, and for fields that concern only a portion of ART cycles. Less attention was dedicated to economic analysis and barriers to access, or to knowledge of and attitudes. International studies provide an opportunity to expand and diversify the scope of ELSI research. Conclusion We call on the research community to promote international collaborations, focus on less explored regions, and divert more attention to questions of cost, access, knowledge, and attitudes.

show abstract

“…analysed more than 26,000 articles on ART and couple infertility published between 2005 and 2016, and reported 'male factor' as the second largest macro-category, next to techniques in the field of human ART (Garcia et al, 2019). Furthermore, the impact of sperm DNA fragmentation in ART research is also reportedly receiving increased attention (Baskaran et al, 2019).…”

Section: Introductionmentioning

confidence: 99%

A scientometric analysis of research publications on male infertility and assisted reproductive technology

et al. 2020

View full text Add to dashboard Cite

Assisted reproductive technologies (ART) are considered as one of the primary mana gement options to address severe male factor infertility. The purpose of this study was to identify the research trends in the field of male infertility and ART over the past 20 years (2000-2019) by analysing scientometric data (the number of publications per year, authors, author affiliations, journals, countries, type of documents, subject area and number of citations) retrieved using the Scopus database. We used VOS viewer software to generate a network map on international collaborations as well as a heat map of the top scientists in this field. Our results revealed a total of 2,148 publications during this period with Cleveland Clinic Foundation contributing the most (n = 69). The current scientometric analysis showed that the research trend on ART has been stable over the past two decades. Further in-depth analysis revealed that density gradient centrifugation (46%) and intracytoplasmic sperm injection (59.2%) are the most reported techniques for sperm separation and ART, respectively. Additionally, azoospermia was the most studied clinical scenario (60.6%), with majority of articles reporting pregnancy rate (47.25%) as the primary reproductive outcome for ART. This study provides insight into the current focus of research in the area of male infertility and ART as well as the areas that require further research in future.

show abstract

Mapping research in assisted reproduction worldwide

Cited by 7 publications

References 18 publications

Hypertension and Reproduction

Hypertension and Reproduction

Mapping international research output within ethical, legal, and social implications (ELSI) of assisted reproductive technologies

A scientometric analysis of research publications on male infertility and assisted reproductive technology

Contact Info

Product

Resources

About