Mapping protein–exopolysaccharide binding interaction inStaphylococcus epidermidisbiofilms by live cell proximity labeling
Luan H. Vo,
Steven Hong,
Kaitlyn E. Stepler
et al.
Abstract:Bacterial biofilms consist of cells encased in an extracellular polymeric substance (EPS) composed of exopolysaccharides, extracellular DNA, and proteins that are critical for cell–cell adhesion and protect the cells from environmental stress, antibiotic treatments, and the host immune response. Degrading EPS components or blocking their production have emerged as promising strategies for prevention or dispersal of bacterial biofilms, but we still have little information about the specific biomolecular interac… Show more
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