Mapping between HAQ-DI and EQ-5D-5L in a Chinese patient population

Abstract

ObjectivesIn order to address the current deficiency of health utility evidence relevant for economic evaluations involving treatments for rheumatoid arthritis (RA) in the Chinese setting, this study aims to develop a mapping algorithm linking the Health Assessment Questionnaire (HAQ) and EQ-5D-5L in a Chinese population of patients with RA.MethodsAn estimation sample was obtained from a cross-sectional study that collected HAQ, the pain Visual Analogue Scale, and EQ-5D-5L in RA patients in two tertiary referral hospitals in China. Mapping algorithms were derived in this study using two alternative regression methods: the beta regression and a multivariate ordered probit regression. The internal validity of the mapping algorithms was assessed in each case by calculating predictive performance using a bootstrapping procedure.ResultsOf the several algorithms developed using these data, predictive performance was shown to be better when VAS pain was included as a predictor and when the multivariate ordered probit regression method was used, rather than the beta regression method. The algorithms developed were shown to be comparable, in terms of predictive performance, to existing mapping studies despite the small sample size of the estimation data.ConclusionIt is hoped that the availability of these algorithms will facilitate the development of cost-effectiveness studies evaluating RA treatments in the Chinese health care setting.Electronic supplementary materialThe online version of this article (10.1007/s11136-018-1925-1) contains supplementary material, which is available to authorized users.

Health‐related quality of life in rheumatoid arthritis: Systematic review and meta‐analysis of EuroQoL (EQ‐5D) utility scores from Asia

“…Thirty‐one studies reported utility scores of RA patients 22‐24,34‐42,45,47‐63,65 . The pooled mean EQ‐5D score was 0.66 (95% CI 0.63‐0.69) with high heterogeneity I 2 = 99.65% (Figure 2A).…”

“…Thirty-one studies reported utility scores of RA patie nts. [22][23][24][34][35][36][37][38][39][40][41][42]45,[47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62][63]65 The pooled mean EQ-5D score was 0.66 (95% CI 0.63-0.69) with high heterogeneity I 2 = 99.65% (Figure 2A).…”

Current Status of Research on the Mapping Function of Health Utility Values in the Asia Pacific Region: A Systematic Review

“…Some researchers studied the mapping model between generic scales, with 10 retrieved articles [22][23][24][25][26][27][28][29][30][31] belonging to this category.…”

“…Patton et al 30 conducted a study on mapping the Health Assessment Questionnaire (HAQ) to EQ-5D-5L preferences by using the data collected from 130 RA patients in China.…”

Mapping health assessment questionnaire disability index onto EQ-5D-5L in China

“…Up to now, a large number of researches have demonstrated that the value of HAQ-DI can be converted into HUV through mapping (12)(13)(14)(15)(16)(17)(18)(19)(20)(21). In Most researches, EQ-5D-3L was chosen as the target scale and the HAQ-DI total score as a single independent variable.…”