2000
DOI: 10.1016/s0140-6736(00)02442-9
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Map-making and myth-making in Broad Street: the London cholera epidemic, 1854

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Cited by 139 publications
(72 citation statements)
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“…To find the optimum over the whole arrangement A, we need to determine Formula 3 for every cell, which means that we determine the six a i and the six b i coefficients. Of course, we can just do this from scratch for each cell individually, but that could require up to O(N) time per cell, since the cluster window belonging to each cell could intersect up to O(N) edges of P. 3 This then leads to a total of O(NK) time (where K is the complexity of the arrangement). We can do better by traversing the cells of the arrangement from cell to adjacent cell while maintaining some information.…”
Section: Computing the Optimal Placement In The Homogeneous Modelmentioning
confidence: 99%
See 1 more Smart Citation
“…To find the optimum over the whole arrangement A, we need to determine Formula 3 for every cell, which means that we determine the six a i and the six b i coefficients. Of course, we can just do this from scratch for each cell individually, but that could require up to O(N) time per cell, since the cluster window belonging to each cell could intersect up to O(N) edges of P. 3 This then leads to a total of O(NK) time (where K is the complexity of the arrangement). We can do better by traversing the cells of the arrangement from cell to adjacent cell while maintaining some information.…”
Section: Computing the Optimal Placement In The Homogeneous Modelmentioning
confidence: 99%
“…Analyzing the geographic nature of disease cases has been a key factor in finding the source of many outbreaks. Since the famous case of geographical analysis of John Snow in 1854 [3,29], numerous examples have been documented in the literature of several fields like epidemiology, public health, preventive medicine, and medical geography.…”
Section: Introductionmentioning
confidence: 99%
“…The original impetus for the sewer network was likely driven by overblown rhetoric and unfair criticism of urban institutions by individuals such as Edwin Chadwick, and relied on an entirely incorrect understanding of disease vector biology [6,7]. While there are heroes that emerge from the story, scientists who analyzed the data and made correct determinations (e.g., John Snow), the methodology and influence attributed to them has become apocryphal [6,8,9]. When first applied, the retrospectively "right" decision, isolating humans from their waste, was undermined by the fact that dramatically improving hydrologic connectivity between London privy pots and the Thames introduced much more sewage to drinking water sources.…”
Section: Human Decisions and Water Usementioning
confidence: 99%
“…The history of medicine is replete with astute clinical observations that have led to major scientific breakthroughs. The classic example in public health is one physician's observation that cholera cases in London were directly related to the distance a person lived from a certain public well (2) . This observation was made at a time when microbiology did not yet exist.…”
Section: International Journal Of Therapeutic Massage and Bodywork-vomentioning
confidence: 99%