We study the propagation of Rydberg slow light polaritons through an atomic medium in the regime where the dispersion relation for the polaritons is well described by the slow light velocity alone. In this regime, the quantum many-body problem can be solved analytically for arbitrary shape of the atomic cloud. We demonstrate the connection of Rydberg polaritons to the behavior of a conventional Kerr nonlinearity for weak interactions and determine the leading quantum corrections for increasing interactions. We propose an experimental setup which allows one to measure the effective two-body interaction potential between Rydberg polaritons as well as higher-body interactions. Our work shows that the locality and causality based no-go theorems for quantum gates do not apply to setups based on Rydberg polaritons.A natural mechanism for an interaction between photons is provided by the Kerr nonlinearity of conventional materials and is well described within a classical theory for high intensities of the fields [1]. On the other hand, a strong interaction between individual photons would pave the way towards ultralow-power all-optical signal processing [2, 3], which in turn has important applications in quantum information processing and communication [4][5][6][7]. First attempts to quantize the phenomenological set of equations for a classical Kerr nonlinearity failed due to locality of the interaction and purely linear dispersion [8-10], while adding ad hoc a non-local response in time resolved this problems [11]. However, this approach also necessitates a strong noise term, and it was argued that the decoherence induced by this noise term leads to a no-go theorem for quantum two qubit gates based on propagating photons in a local nonlinear media [12], which motivated the research on several different approaches [13][14][15][16][17]. In turn, it has recently been proposed to use Rydberg slow light polaritons for the generation of a quantum two qubit gate [18,19], which seem to be in contradiction to the above no-go theorem. In the present manuscript, we resolve this puzzle by demonstrating that the microscopic description of Rydberg polaritons also provides a consistent quantum theory of a Kerr nonlinearity without the necessity to introduce a strong noise term.Rydberg slow light polaritons have emerged as a highly promising candidate to engineer strong interactions between optical photons with a tremendous recent experimental [16,[20][21][22][23][24][25][26][27][28][29][30] and theoretical [19,[31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49] progress. A variety of applications were shown such as a deterministic single photon source [50], an atomphoton entanglement generation [51], as well as a single photon switch [27] and transistors [26,28,29]. Moreover, the regime of strong interaction between photons has been experimentally demonstrated leading to a medium transparent only to single photons [22], as well as the appearance of bound states for photons [25]. From theoretical point of vie...