Manual Liquid Based Cytology in Breast Fine Needle Aspiration – Comparison with the Conventional Smear

Mahinderu, Karan; Nandini, N M; Kishore, Arnaw; Singh, Anil Kumar

doi:10.9790/0853-150771724

Cited by 2 publications

(2 citation statements)

References 29 publications

(52 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In Mahinderu et al . 's study,[8] sensitivity and specificity for both LBC and CS were 95.2% and 100%, respectively. PPV and NPV for manual LBC and CS were 100% and 96.9%, respectively.…”

Section: Discussionmentioning

confidence: 99%

“…The other most important advantage of LBC preparations is the residual sample availability for additional ancillary techniques, such as immunocytochemistry (ICC), flow cytometry and molecular biology. [8] However, our experience in interpretation of cell changes in liquid-based preparation compared to conventional method is limited, so the aim of our study was to assess the diagnostic efficacy of LBC and compare it with the conventional preparation in breast FNA samples.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of liquid-based and conventional cytology in diagnosis of breast mass

Kord

Mokhtari

Tahmasebi

2019

J Cytol

View full text Add to dashboard Cite

Background:Among all diagnostic techniques for breast lesions, fine-needle aspiration (FNA) is the simplest, most reliable and cheapest one.Aim:To compare liquid-based and conventional cytology in diagnosis of breast mass.Materials and Methods:About 101 patients with breast mass were enrolled. The aspirated materials were divided into two parts. One was poured into a liquid medium and the other part was directly spread on clean glass slides. Conventional and liquid-based preparations were compared using several criteria including adequacy (presence of the epithelial cluster or myoepithelial cells), overall cellularity, presence of single epithelial cells, presence of myoepithelial cells, epithelial architecture, nuclear detail, nuclear atypia and inflammatory/proteinaceous background and final diagnosis.Results:Among 101 cases, 85 (84.1%) were malignant and 16 (15.9%) were benign. Conventional and liquid-based cytology were similar according to adequacy (P = 0.65), cellularity (P = 0.13), epithelial architecture (P = 0.15), presence of myoepithelial cells (P = 0.61), nuclear detail (P = 0.57) and nuclear atypia (P = 0.44), while there were a significant difference between the two methods according to the presence of single epithelial cells (P < 0.001) and background (P < 0.001).Conclusion:Liquid-based cytology of breast specimens is an accurate diagnostic tool with high diagnostic yield in benign and malignant lesions.

show abstract

“…In Mahinderu et al . 's study,[8] sensitivity and specificity for both LBC and CS were 95.2% and 100%, respectively. PPV and NPV for manual LBC and CS were 100% and 96.9%, respectively.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison of liquid-based and conventional cytology in diagnosis of breast mass

Kord

Mokhtari

Tahmasebi

2019

J Cytol

View full text Add to dashboard Cite

show abstract

Comparing the Effectiveness of Liquid Based Cytology (Lbc) With Conventional Pap Smear: A Prospective Study

Saxena

Rai

Shrivastava

et al. 2022

PIJR

View full text Add to dashboard Cite

Background: Cervical cancer is unique among human cancers which is mostly attributable to infection. Conventional PAP smear method is most effective for prevention and detection of cervical cancer but the accuracy of this method is low.This PAP smear now evolved to Liquid Based Cytology (LBC). Method:All the patients visiting Gynaecology OPD who fulfilled the inclusion Criteria in the duration starting from 1 January 2020 to 30 June 2021 in the Department of Pathology of Gajra raja Medical College, Gwalior (MP) were included in this study. 50 atypical smears by Conventional PAP test were then collected and these cases were subjected to Eziprep Liquid Based Cytology and Conventional PAP smear in private laboratory setup after taking history and clinical examination. The smears were studied by using 7 morphological parameters. Result: Smears were analysed for adequate cellularity, clean background, uniform distribution of cells,cellular overlapping,inflammation,distinct cell border,nuclear irregularity and then categorise by Bethesda reporting system.The results were significant only for clean background,uniform distribution of cells,cellular overlapping and inflammation. Conclusion: Results of cervical cytology smears by both methods showed that LBC provides more representative sample with reduced obscuring material,improved clarity allowing better morphological evaluation.

show abstract

Manual Liquid Based Cytology in Breast Fine Needle Aspiration – Comparison with the Conventional Smear

Cited by 2 publications

References 29 publications

Comparison of liquid-based and conventional cytology in diagnosis of breast mass

Comparison of liquid-based and conventional cytology in diagnosis of breast mass

Comparing the Effectiveness of Liquid Based Cytology (Lbc) With Conventional Pap Smear: A Prospective Study

Contact Info

Product

Resources

About