Manual acupuncture alleviates bladder dysfunction by up-regulating expression of NGF and its receptors in bladder tissue of diabetic neurogenic bladder rats
Abstract:Objective
To investigate the effect of manual acupuncture on diabetic neurogenic bladder (DNB) rats through the protein and mRNA expression of nerve growth factor (NGF), tropomyosin receptor kinase A (TrkA), p75neurotrophinreceptor (p75NTR) in bladder tissue, as well as the levels of substance P (SP) and calcitonin gene-related peptides (CGRP).
Methods
A DNB rat model was induced using intraperitoneal injection of streptozotocin (STZ). The rats were randomly divided into a blank control group, a model group,… Show more
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