Mantle cell lymphoma-like solitary polypoid tumor of the esophagus: a case report

Mori, Takahiro; Komeno, Takuya; Ohtani, Haruo

doi:10.1186/1757-1626-2-6646

Cited by 2 publications

(3 citation statements)

References 9 publications

(12 reference statements)

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“…The median overall survival was 12 months with excellent prognosis of MALT lymphoma compared with DLBCL [ 6 ]. Other histological types of PEL have also been described in the literature including Burkitt's lymphoma [ 7 ], mantle cell [ 8 ], anaplastic [ 9 , 10 ], T-cell lymphoma [ 11 ], Hodgkin's lymphoma [ 2 , 12 ], and true histiocytic lymphoma [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Primary Esophageal Lymphoma: A Histopathological Experience from Two Tertiary Hospitals, Western Saudi Arabia

Al-Maghrabi

2023

Gastroenterology Research and Practice

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Background. Primary esophageal lymphoma (PEL) is a rare disorder. The objective of this study was to document the clinicopathological features of PEL at two tertiary hospitals in the western region of the Kingdom of Saudi Arabia. Methods. All PELs diagnosed between May 2002 and June 2022 were retrieved. Histopathological and immunohistochemical slides were reviewed. Additional immunohistochemistry stains were performed in selected cases. Follow-up data were collected. Results. There were only eight cases of PEL in the records of the two hospitals. The age of the patients ranged between 50 and 74 years (median 62 years and mean 62.5 years). There were six males (80%) and two females (20%). None of the patients were immunocompromised or had human immunodeficiency virus (HIV) infection. The clinical manifestation included dysphagia and loss of weight. Six cases were diffuse large B-cell lymphoma (DLBCL), and two were low-grade mucosa-associated lymphoid tissue lymphoma. Conclusion. PEL is an extremely rare disease with male predominance. DLBCL is the most common pathological type in our community. There was no relation to immune status or HIV infection in this series. Clinical presentations were typically dysphagia with weight loss. Further reporting of PEL cases might help explain this disease and improve its diagnosis and management.

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Section: Discussionmentioning

confidence: 99%

Primary Esophageal Lymphoma: A Histopathological Experience from Two Tertiary Hospitals, Western Saudi Arabia

Al-Maghrabi

2023

Gastroenterology Research and Practice

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“…Esophageal NK/T-cell lymphoma is primarily in male patients, with a male to female ratio of 5:1 ( 4 – 8 ). Patients with esophageal lymphoma may present with dysphagia ( 3 ), odynophagia ( 14 ) and weight loss ( 9 ). Additional clinical features include fever, night sweats ( 15 ), pharyngeal pain ( 16 ) and epigastric pain ( 17 ), and generalized weakness and dizziness ( 18 ) may also be present.…”

Section: Discussionmentioning

confidence: 99%

“…It primarily occurs in the nasal/nasopharyngeal region, accounting for ~75% of cases, with 4% occurring in the skin and 6% in the gastrointestinal tract ( 2 ). However, primary lymphoma located within the esophagus is markedly rare, with an incidence of <1% of all patients with lymphoma ( 3 ) and the majority of such cases are NHL. Furthermore, to the best of our knowledge, only 6 cases of primary NK/T-cell lymphoma of the esophagus have been identified ( 4 – 8 ).…”

Section: Introductionmentioning

confidence: 99%

Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report

2017

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Primary esophageal natural killer (NK)/T-cell lymphoma is a markedly rare tumor. There were only 6 cases of the disease identified prior to June 2015. In the present study, the aforementioned cases were validated, and relevant computed tomography (CT) results and clinical features of primary esophageal NK/T-cell lymphoma were determined, to increase awareness of this type of tumor. CT features and clinical presentations of a patient with pathologically confirmed esophageal NK/T-cell lymphoma was analyzed. The patient exhibited non-specific clinical symptoms and CT images revealed diffuse thickening of the entire length of the esophagus. The patient received cycles of systemic chemotherapy and subsequent chest CT images demonstrated prompt and marked shrinkage of the tumor. At the time of writing, the patient has survived for 24 months and experiences a good quality of life without postprandial fullness or difficulty swallowing solid food. In addition, the characteristics of 6 patients with complete clinical features of this type of tumor, on the basis of a review of published studies (online PubMed, Medline, Google Scholar, Chinese Biomedicine Database and China Journal Full Text Database search), were retrospectively analyzed. Although primary esophageal NK/T-cell lymphoma is a markedly rare tumor, it is considered to be included in differential diagnosis of patients presenting with a fungal or viral infection, therapy-related mucositis or reflux esophagitis. The final diagnosis of primary esophageal NK/T-cell lymphoma is on the basis of a combination of clinical, CT and histopathological results.

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Mantle cell lymphoma-like solitary polypoid tumor of the esophagus: a case report

Cited by 2 publications

References 9 publications

Primary Esophageal Lymphoma: A Histopathological Experience from Two Tertiary Hospitals, Western Saudi Arabia

Primary Esophageal Lymphoma: A Histopathological Experience from Two Tertiary Hospitals, Western Saudi Arabia

Radiological and clinical features of primary NK/T-cell lymphoma involving the whole length of the esophagus: A case report

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