Manometric Abnormalities in the Postural Orthostatic Tachycardia Syndrome: A Case Series

Abstract

In this cohort of POTS patients with gastrointestinal symptoms, there is a high prevalence of abnormal manometric and radiographic findings suggestive of dysmotility.

Gastrointestinal disorders in joint hypermobility syndrome/Ehlers‐Danlos syndrome hypermobility type: A review for the gastroenterologist

“…Postural tachycardia syndrome, independent of EDS status, is associated with GI symptoms and with dysmotility of the stomach, small bowel, and colon, as demonstrated by a number of previous studies . Patients with GI symptoms who meet the criteria for JHS/EDS‐HT have significantly higher autonomic scores for orthostatic domains ( P <.001) compared to patients without JHS/EDS‐HT …”

Mechanisms underlying reflux symptoms and dysphagia in patients with joint hypermobility syndrome, with and without postural tachycardia syndrome

“…GI symptoms such as nausea, vomiting and bloating, 11,12 and GI dysmotility. [12][13][14] No existing studies involving upper GI physiology in JHS patients have subtyped them according to PoTS status.…”

“…A large proportion of patients with JHS also suffer with postural tachycardia syndrome (PoTS), a form of orthostatic intolerance typically presenting with palpitations, dizziness, shortness of breath, and syncope which can occur postprandially and with postural changes. Independent of JHS, the presence of PoTS is associated with upper GI symptoms such as nausea, vomiting and bloating, and GI dysmotility . No existing studies involving upper GI physiology in JHS patients have subtyped them according to PoTS status.…”

Antroduodenal Manometry Is Abnormal in Children Presenting With Orthostatic Intolerance and Gastrointestinal Symptoms

“…Abnormal gastrointestinal motility patterns were identified using previously reported parameters. (14) 1. Myopathy was diagnosed if the amplitude of contractions was below 40 mmHg in the antrum, and below 10 mmHg in the duodenum 2.…”