Mannitol Protects against Oxidation by Hydroxyl Radicals

Shen, Bo; Jensen, Richard G.; Bohnert, Hans J.

doi:10.1104/pp.115.2.527

Cited by 364 publications

(206 citation statements)

References 20 publications

Supporting

Mentioning

196

Contrasting

Unclassified

Order By: Relevance

“…Previous studies have shown that osmolytes, including polyols, have free radical scavenging properties (Shen et al, 1997;Smirnoff and Cumbes, 1989). Most of these results, however, were from in vitro experiments using relatively high concentrations of compatible solutes.…”

Section: Function Of Polyol Moleculescontrasting

confidence: 41%

Physiological Roles of Polyols in Horticultural Crops

Kanayama

2009

J. Japan. Soc. Hort. Sci.

View full text Add to dashboard Cite

Sucrose is generally considered the primary photosynthate in plants; however, many horticultural crops, including rosaceous fruit trees, synthesize and use polyols (sugar alcohols). This review describes recent progress in physiological research on the metabolism and transport of sorbitol in rosaceous fruit trees, and of mannitol, another common polyol, in horticultural crops. Studies on various polyols other than sorbitol (in rosaceous fruit trees) and mannitol are then described. Polyols play a role not only in the translocation and storage of photosynthates but also in biotic and abiotic responses in many horticultural crops; therefore, this review also provides insights into the effects of polyol metabolism on the biochemical mechanisms of pathogenicity and environmental stress tolerance, including a novel strategy for engineering stress tolerance.

show abstract

Section: Function Of Polyol Moleculescontrasting

confidence: 41%

Physiological Roles of Polyols in Horticultural Crops

Kanayama

2009

J. Japan. Soc. Hort. Sci.

View full text Add to dashboard Cite

show abstract

“…Although some stresses, such as pathogen elicitors, drought and cadmium, have been shown to cause HR generation in plants (Becana and Klucas, 1992;Moran et al, 1994;Shen et al, 1997;Van Doorslaeder et al, 1999), the effect of salinity has not been studied (Chung et al, 2008). Electron paramagnetic resonance (EPR) spectroscopy is one of the most accurate and sensitive techniques for the detection of radicals in living systems (Halliwell and Gutteridge, 1999).…”

Section: Salt-induced Generation Of Hrs In Intact Rootsmentioning

confidence: 99%

Arabidopsis root K+-efflux conductance activated by hydroxyl radicals: single-channel properties, genetic basis and involvement in stress-induced cell death

Demidchik

Cuin

Svistunenko

et al. 2010

Journal of Cell Science

439

369

View full text Add to dashboard Cite

SummaryReactive oxygen species (ROS) are central to plant stress response, signalling, development and a multitude of other processes. In this study, the plasma-membrane hydroxyl radical (HR)-activated K + channel responsible for K + efflux from root cells during stress accompanied by ROS generation is characterised. The channel showed 16-pS unitary conductance and was sensitive to Ca 2+ , tetraethylammonium, Ba 2+ , Cs + and free-radical scavengers. The channel was not found in the gork1-1 mutant, which lacks a major plasma-membrane outwardly rectifying K + channel. In intact Arabidopsis roots, both HRs and stress induced a dramatic K + efflux that was much smaller in gork1-1 plants. Tests with electron paramagnetic resonance spectroscopy showed that NaCl can stimulate HR generation in roots and this might lead to K + -channel activation. In animals, activation of K + -efflux channels by HRs can trigger programmed cell death (PCD). PCD symptoms in Arabidopsis roots developed much more slowly in gork1-1 and wild-type plants treated with K + -channel blockers or HR scavengers. Therefore, similar to animal counterparts, plant HR-activated K + channels are also involved in PCD. Overall, this study provides new insight into the regulation of plant cation transport by ROS and demonstrates possible physiological properties of plant HR-activated K + channels.

show abstract

“…In addition to these functions, polyols also function as oxygen radical scavengers. For example, mannitol was found in vitro to act as a scavenger of reactive oxygen species (Shen et al, 1997), thereby protecting the proteins from oxidative damage in drought stressed plants. Smirnoff and Cumbes (1989) found that mannitol, sorbitol, glycerol, ononitol and pinitol were all active scavengers.…”

mentioning

confidence: 99%

Potential of the Common Ice Plant,Mesembryanthemum crystallinumas a New High-Functional Food as Evaluated by Polyol Accumulation

Agarie

Kawaguchi

Kodera

et al. 2009

Plant Production Science

View full text Add to dashboard Cite

: We measured the concentration of polyols (pinitol, ononitol, and myo-inositol), which are known to have health-promoting and/or disease-preventing functions, in the common ice plant (Mesembryanthemum crystallinum L.) cultured under salt-and drought-stressed treatments. In NaCl-treated plant the concentration of pinitol/ononitol increased with increasing NaCl concentration in culture solution. The maximal concentration was 3.6 mg g -1 FW, which was found in the shoot top, followed by small side shoots (2.1 mg g -1 FW) of mature plants grown with 400 mM NaCl for 35 ds. The drought stress also accelerated the accumulation of pinitol/ ononitol. The maximal concentration was 1.2 mg g -1 FW, which was found in the shoot top of plants under the stress for 25 ds. The myo-inositol increased in salt-stressed plants at 3 ds after the start of the treatment and then decreased with the lapse of time during stress. The concentration of polyols in the ice plant was comparable to that in the other species reported to accumulate polyols at high levels. Radical scavenging activity evaluated by DPPH assay was increased two-fold by 400 mM NaCl treatment, which was twice as high as that in the leaves of lettuce (Lactuca sativa L.). These results indicated the high potential of the ice plant as a polyol-rich highfunctional food.

show abstract

Mannitol Protects against Oxidation by Hydroxyl Radicals

Cited by 364 publications

References 20 publications

Physiological Roles of Polyols in Horticultural Crops

Physiological Roles of Polyols in Horticultural Crops

Arabidopsis root K+-efflux conductance activated by hydroxyl radicals: single-channel properties, genetic basis and involvement in stress-induced cell death

Potential of the Common Ice Plant,Mesembryanthemum crystallinumas a New High-Functional Food as Evaluated by Polyol Accumulation

Contact Info

Product

Resources

About