Mannans and mannan oligosaccharides (MOS) from Saccharomyces cerevisiae – A sustainable source of functional ingredients

Influence of Dissolved Oxygen Level on Chitin–Glucan Complex and Mannans Production by the Yeast Pichia pastoris

“…Galinari et al [25], for example, obtained 13 wt% of mannans content from Kluyveromyces marxianus biomass. A mannoprotein content of 12-18 wt% was also reported by Faustino et al [26] for Saccharomyces cerevisiae. This higher mannans production observed at the 15% DO level was also reflected in the highest mannans productivity (3.02 g/(L. day)) and mannans yield (0.09 gm/gs) (Table 1).…”

“…The DO level of 15% also revealed to be the best oxygen level condition for mannans production, since it enabled the highest polysaccharide content (20 wt%) and concentration (5.32 g/L) (Table 1). Lower values (4-18 wt%) have been reported for mannans production by other yeasts and fungi [25][26][27], which demonstrates the advantage of using P. pastoris as a yeast mannans producer. Galinari et al [25], for example, obtained 13 wt% of mannans content from Kluyveromyces marxianus biomass.…”

Bioactive Ingredients Obtained from Agro-industrial Byproducts: Recent Advances and Innovation in Micro- and Nanoencapsulation

“…Prebiotics are substrates that are selectively used by the host microbiota, promoting the growth and metabolic activity of different microorganism groups, conferring a health benefit . Prebiotics are generally non-digestible oligosaccharides with a degree of polymerization between 4 and 30 that can be classified on the basis of their structure on fructooligosaccharides (FOS, fructose linked with a terminal glucose by β–2–1 bonds, with repetition of inulobiose, levanobiose, and sucrose), galactooligosaccharides (GOS, galactose linked by glycosidic bonds β–1–2, β–1–3, β–1–4, and β–1–6 with a terminal glucose), human milk oligosaccharides (HMO, composed of glucose, galactose, acetylglucosamine, fructose, or sialic acid with lactose at their reducing end), mannanoligosaccharide (MOS, obtained from partial hydrolysis of mannan polysaccharides; they can present an α–1–6 or β–1–4 bond), xylooligosaccharide (XOS, xylose residues linked through β–1–4 bonds), and arabinoxylooligosaccharide (AXOS, xylose backbone linked through β–1–4 bonds with arabinose substitution), to name a few, but other non-carbohydrate substrates are also recognized as prebiotics, such as conjugated linoleic acid (CLA), PUFAs, and polyphenols. − Byproducts are a great source of prebiotics (Table ), with different extraction techniques, such as thermal treatments, enzymatic extraction, and alkaline extraction, among others, and also throughout solid fermentation with fungi. The extraction technique and source have a great influence on the biological activity of these prebiotics.…”

Characterization and Antioxidant Activity of Mannans from Saccharomyces cerevisiae with Different Molecular Weight

“…They are very important biomacromolecules in life activities and play critical roles in cell–cell communication and molecular recognition in the immune system. Saccharomyces cerevisiae (Brewer’s yeast) is described as a generally recognized as safe (GRAS) microorganism, and also contains nutritional value and bioactive properties [ 1 , 2 ]. Mannans are essential structural components of the yeast cell wall, and are generally associated with proteins in the outer and inner membrane.…”

“…Yeast mannans exhibit various health benefits, such as immunomodulatory activity, radical-scavenging abilities collateral sensitivity, prebiotic activity, etc. [ 1 ]. These nutritional and bioactive properties have increasingly attracted the attention of the food, pharmaceutical, and cosmetic industries.…”