Manipulation of single fine particle in liquid by electrical force in combination with optical pressure

Mizuno, Akira; Imamura, Makoto; Hosoi, Kazuo

doi:10.1109/28.67545

Cited by 18 publications

(8 citation statements)

References 13 publications

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“…The mode (ii) of impact damage involves the light pressure generated by the emission of photons (Mizuno et al, 1991;Wang, 1991). When a photon with mass m ϕ is emitted and moves at light velocity c with wavelength and frequency , the mass of the photon can be related to Plank's constant h as m ϕ = h /c 2 and its momentum can be expressed as m ϕ c = h/ .…”

Section: Impact Damagementioning

confidence: 99%

Micro-machinability of monocrystal silicon by direct etching using excimer laser

Yuan

2008

Journal of Materials Processing Technology

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Section: Impact Damagementioning

confidence: 99%

Micro-machinability of monocrystal silicon by direct etching using excimer laser

Yuan

2008

Journal of Materials Processing Technology

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“…Several technologies of cell positioning/trapping [12] have been reported in recent years, for example, devices based on optical force [13], magnetic force [14], and electrical force [15]. Vacuum-based cell trapping is appealing since low vacuum levels prove effective and do not produce undesired biological complications for further cellular development, as reported in our previous work [16], [17].…”

Section: A Overall Designmentioning

confidence: 95%

Batch Transfer of Zebrafish Embryos Into Multiwell Plates

Zhang

Lü

Gelinas

et al. 2011

IEEE Trans. Automat. Sci. Eng.

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Abstract-This paper reports a prototype cooperative robotic system capable of transferring zebrafish embryos in parallel and depositing a single embryo per well in a 96-well microplate. A cell holding device was developed to trap multiple embryos in a regular pattern. The cell holding device and a microplate were positioned and aligned along multiple axes by the system. Embryo release strategies were systematically studied and compared. Experiments demonstrated that out of the 1056 zebrafish embryos used in experiments (i.e., 44 times parallel transfer into 11 96-well plates), 996 wells were successfully filled with one and only one zebrafish embryo, representing a success rate of 94.3%. Further experiments confirmed that the transferred embryos were able to develop into zebrafish with 100% survival rate.Note to Practitioners-Biological experiments and drug screen require the transfer of individual zebrafish embryos into standard multiwell microplates. Manually pipetting one and only one embryo into each well is tedious and time consuming. Different from the only commercial system for automated zebrafish embryo transfer, which is based on conventional, expensive flow cytometry, the proof-of-principle system reported in this paper utilizes a cell immobilization device and a cooperative robotic mechanism for parallel transfer of zebrafish embryos. The system architecture and transfer techniques promise efficient, cost-effective zebrafish embryo transfer for applications requiring molecule tests on a high number of cells.Index Terms-Batch transfer, control and alignment, cooperative robotic mechanism, drug screen, high-throughput screen (HTS), multiwell microplate, zebrafish embryo.

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“…Microhandling can be carried out by contact methods, mostly mechanical [2,4,7,9,13,16,18,[22][23][24][25][26], or various non-contact methods such as optical pressure [1,3,12,20], acoustic and ultrasonic wave [10,[33][34][35], magnetic field [18,36], electrical field [21], or a combination of several methods. The environment of microhandling can be air, liquid or vacuum (often in an SEM).…”

Section: Introductionmentioning

confidence: 99%

Automatic dextrous microhandling based on a 6-DOF microgripper

Zhou¹,

Korhonen²,

Laitinen³

et al. 2006

Journal of Micromechatronics

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The demand for automatic quality inspection of individual micro components increases strongly in micro optoelectronics industry. In many cases, quality inspection of those micro components needs dexterous microhandling. However, automatic dexterous handling of micro components is a very challenging issue which is barely explored. This paper presents a high-DOF (degrees of freedom) automatic dexterous handling and inspection system for micro optoelectronic components using a novel 6-DOF piezoelectric microgripper. The control system includes three hierarchical layers: actuator control layer, motion planning layer, and mission control layer. Machine vision is applied in automatic manipulation. The performance of the system is demonstrated in a vision based automatic inspection task for 100 300 300 × × μm sized optoelectronics components and reached a cycle time of s 3 . 0 1 . 7 ± .

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Manipulation of single fine particle in liquid by electrical force in combination with optical pressure

Cited by 18 publications

References 13 publications

Micro-machinability of monocrystal silicon by direct etching using excimer laser

Micro-machinability of monocrystal silicon by direct etching using excimer laser

Batch Transfer of Zebrafish Embryos Into Multiwell Plates

Automatic dextrous microhandling based on a 6-DOF microgripper

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