Manifestations of drug reactions urticaria and cutaneous necrotizing venulitis

Drug Allergy: When, Where, Why, and Who?

“…All too often, the patient has relied upon a mother's admonition of 30 years prior or has confused the natural course of illness with an unexpected reaction. Whereas urticaria and anaphylaxis are bona fide allergic responses, nausea and flatulence are frequently unassociated problems 3 . To complicate the situation, a patient can develop a true dermatologic problem coincident with medication use; a patient might have recurrent erythema multiforme due to herpes simplex labialis, but penicillin, which should not have been prescribed for the accompanying viral pharyngitis, was not a culprit 4–6 …”