Manifestations and clinical phenotypes are not specific enough to predict SARS‐CoV‐2 infection in symptomatic children

Abstract

The massive number of infected individuals who have to be tested for SARS-CoV-2 has attracted the attention to novel diagnostic approaches, focusing on symptom-based screening. 1 Some countries have emerged national testing policies, but a large number of positive children do not report any of the included symptoms in those guidelines. 2 This study aimed to analyse symptoms/signs associated with SARS-CoV-2 infection among symptomatic children screened for COVID-19 and define clinical phenotypes that could differentiate COVID-19 from other infections. We performed a cross-sectional multicentre study, nested in a prospective, observational cohort, EPICO-AEP (Epidemiological Study of COVID-19 in Children of the Spanish Society of Paediatric). 3 Eligible participants were children <18 years old with symptoms compatible with SARS-CoV-2 infection lasting ≤5 days (Table 1) 1 attended at 10 emergency departments in Spain, from 2 March to 15 June 2021 (third epidemic wave in Spain; >70% SARS-CoV-2 isola-

Corrigendum

“…It has come to our attention that there is a typo in the Funding Information in our published article 1 . The incorrect sentence ‘This study was supported by Project PI20/00095, from the Instituto de Salud Carlos III (Ministry of Economy, Industry and Competitiveness) and cofounded by the European Regional Development Fund’, has been replaced with the following information:…”