“…A recent study found that children who received heart transplants (HXT) and subsequent thymectomies before their first birthday had an increased risk of developing AD in conjunction with immunosuppression (Niemeier et al, ). In this study, 9/11 children (82%) with HXT performed before their first birthday developed AD, believed to be due to premature immune maturation selectively inhibiting the Th1 > Th2 inflammatory response (Niemeier et al, ; Shaw, Currie, Koudelka, & Simpson, ). Here, we report the case of a young immunosuppressed heart transplant patient with severe AD successfully treated with dupilumab (Dupixent, Regeneron, and Sanofi).…”