Manifestaciones mucocutáneas y su relación con el recuento de linfocitos T CD4 en pacientes infectados con el virus de inmunodeficiencia humana hospitalizados en Medellín, Colombia

Sanín, Ana María; Londoño, Ángela; Gil, Verónica; Mejía, Ana María; Aguirre, Hernán Darío; Trespalacios, Elsa María Vásquez; Valencia, Catalina; Cardona, Carolina

doi:10.7705/biomedica.6117

Cited by 6 publications

(4 citation statements)

References 23 publications

(32 reference statements)

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“…Almost 90% of HIV-infected patients were noted to have dermatologic conditions associated with the disease and with these skin conditions as being the initial reason for consult. 13 Occurrence of dermatologic conditions can be correlated with the CD4 level of the patient.…”

Section: Introductionmentioning

confidence: 99%

Correlation of whole blood zinc levels, CD4 cell count, HIV disease stage, and dermatologic manifestations among diagnosed HIV patients in a tertiary hospital

Sarne¹,

Gabriel²,

Vista³

et al. 2022

International Journal of Dermatology and Venereology

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Objective: Zinc deficiency is the most common micronutrient abnormality seen in human immunodeficiency virus (HIV) infection. Depletion of CD4 cells is a hallmark of HIV infection. The study aims to determine the association between whole blood zinc levels and CD4 cell count and stage of HIV infection among patients in a tertiary hospital in the Philippines. Methods: Sixty-five newly diagnosed HIV-positive patients of the institution were recruited. Demographic profile, whole blood zinc levels, CD4 cell count level, HIV disease stage, and presence of any dermatologic manifestations were noted. Prevalence of zinc deficiency and correlation between whole blood zinc levels and CD4 cell count were determined. The data were analyzed by chi-square and pearson correlation analysis. Results: Among the 65 patients, overall zinc deficiency was noted at 33.8%. Low CD4 count and HIV disease stage IV participants had the highest percentage of zinc deficiency at 54.6% and 50%, respectively. A correlation coefficient at r = 0.3364 was noted between whole blood zinc levels and CD4 cell count (P = 0.006). Twenty-nine patients presented with dermatologic manifestations, with 10 patients being zinc deficient. Conclusion: A weak positive correlation was seen between zinc levels and CD4 count. There is an increasing frequency of zinc level deficiency with a higher HIV disease stage. Dermatologic manifestations of HIV may be present in both patients with normal and deficient zinc levels.

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Section: Introductionmentioning

confidence: 99%

Correlation of whole blood zinc levels, CD4 cell count, HIV disease stage, and dermatologic manifestations among diagnosed HIV patients in a tertiary hospital

Sarne¹,

Gabriel²,

Vista³

et al. 2022

International Journal of Dermatology and Venereology

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“…It was pointed out that the incidence of disseminated herpes zoster increased with the decrease of CD4 T cells. 18 Catherine et al 19 reported a middle-aged woman without other HIV risk factors. She had severe, disseminated, persistent herpes zoster with a low CD4 T cell count <200/mcL.…”

Section: Discussionmentioning

confidence: 99%

Disseminated Herpes Zoster with Decreased CD4 Counts in a HIV-Infected Patient

Zeng,

Feng,

Yao

et al. 2023

CCID

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Herpes zoster is typically a blister rash involving a single skin group, caused by the reactivation of primary varicella zoster virus infection. Disseminated herpes zoster refers to the presence of more than 20 small blisters outside the primary or adjacent skin, which is rare and usually occurs in individuals with weakened immune function. This case described a patient diagnosed with disseminated herpes zoster, with a decrease in CD4 count (379 cells/mm3) and certain skin lesions. He was subsequently screened positive for HIV. Also, we summarized other studies on the CD4 value of HIV patients with herpes zoster. Overall, for herpes zoster patients with decreased CD4 levels and certain skin manifestations, such as diffuse, ulcerative, or pustular lesions, clinicians should be aware of HIV infection.

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“…People living with HIV are at a higher risk of developing NHL due to their weakened immune system. The risk of developing NHL increases with the degree of immune suppression and other factors such as co-infection with other viruses and lifestyle factors [1,[11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29].…”

Section: Discussionmentioning

confidence: 99%

Aids and Non-Hodgkin Lymphoma: Report of a Case

2023

Int J Virol AIDS

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A 49-year-old male resident of Cancun has the following significant history: full immunization, SARS-CoV-2, 2 AstraZeneca doses, previous hospitalizations on two occasions in the last three years for pneumonia, transfusions in March 2022 for anemia, alcoholism for 29 years at a rate of 14 gr/day suspended 8 months ago. HIV positive for 20 years with intermittent adherence to treatment, currently with a third treatment scheme with ritonavir, darunavir, dolutegravir and tenofobir with emtricitabine.

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Manifestaciones mucocutáneas y su relación con el recuento de linfocitos T CD4 en pacientes infectados con el virus de inmunodeficiencia humana hospitalizados en Medellín, Colombia

Cited by 6 publications

References 23 publications

Correlation of whole blood zinc levels, CD4 cell count, HIV disease stage, and dermatologic manifestations among diagnosed HIV patients in a tertiary hospital

Correlation of whole blood zinc levels, CD4 cell count, HIV disease stage, and dermatologic manifestations among diagnosed HIV patients in a tertiary hospital

Disseminated Herpes Zoster with Decreased CD4 Counts in a HIV-Infected Patient

Aids and Non-Hodgkin Lymphoma: Report of a Case

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